Evidence map›Paper›PMID 29486765›Full record

ArticleTrials2018

Xiangbin prescription for the recovery of gastrointestinal function after abdominal surgery (the XBPRS trial): study protocol for a randomized controlled trial.

Huachan Gan, Jinxuan Lin, Zhi Jiang, Qicheng Chen, Lixing Cao, Zhiqiang Chen

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Influence of acupuncture and moxibustion on gastrointestinal function and adverse events in gastric cancer patients after surgery and chemotherapy: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Review
  3. Article
  4. Xiangbinfang granules enhance gastric antrum motilityWorld journal of gastroenterology · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Huachan GanThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Jinxuan LinThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Zhi JiangThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Qicheng ChenThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Lixing CaoThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China. lixingcao@126.com.
Zhiqiang ChenThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China. zhi57@163.com.
Guangzhou University of Chinese Medicine · CN

Funding

Chinese Medicine Bureau of Guangdong Province NO.12 20164021Guangdong provincial department of science and technology 2014A020212278Science and technology planning project of guangzhou 2014Y2-00048Scientific special expenditure of Guangdong Provincial Hospital of Traditional Chinese Medicine YK2013B2N03
6 · The paper itself

Abstract

backgroundMost patients who undergo abdominal surgery recover bowel movements within a week; however, some suffer prolonged intestinal paralysis or postoperative ileus (POI) leading to complications, such as infection and intestinal adhesions, which can extend hospitalization and increase readmission rates, and consequently increasing healthcare costs. Chinese medicine is effective for accelerating the recovery of gastrointestinal function after abdominal surgery. Xiangbin prescription (XBP) is the standard prescription for this purpose in our hospital; however, randomized controlled trials of it have not yet been conducted. METHODS/

designThis double-blind, randomized controlled clinical trial aims to recruit patients who have undergone abdominal surgery and experienced postoperative dysmotility to evaluate the efficacy and safety of XBP for preventing POI and accelerating recovery. The research will tackle the common problem of slow recovery of gastrointestinal function after surgery. The participants will be patients who undergo laparoscopic radical resection of rectal carcinoma or laparoscopic panhysterectomy of a benign lesion. Primary outcome measures will be time to first flatus, defecation, normal bowel sounds, and liquid/semi-liquid/general diet. Good Clinical Practice (GCP) standards of efficacy and safety will also be evaluated, along with objective investigation of the mechanism of action of ghrelin. DISCUSSION: This pivotal trial will be a standardized, scientific, clinical trial designed to evaluate the use of XBP for the recovery of gastrointestinal function after surgery, and it will conform to international standards for clinical trials for the recognition of traditional Chinese medicine.

trial registrationChinese Clinical Trial Registry, ID: ChiCTR-TRC-14004156 . Registered on 3 January 2014.

Indexed as

AbdomenAdultAgedChinaDefecationDouble-Blind MethodDrugs, Chinese HerbalFemaleFlatulenceHumansHysterectomyIntestinal Pseudo-ObstructionLaparoscopyMaleMiddle AgedRandomized Controlled Trials as TopicDrugs, Chinese HerbalXiangbinFast recoveryGastrointestinal functionPerioperative periodRandomized parallel controlled trialXiangbin prescription

Identifiers

PMID29486765
PMCPMC5830341
OpenAlexW2797682159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.