Evidence map›Paper›PMID 29486752›Full record

ArticleBMC women's health2018

Facing HIV infection and unintended pregnancy: Rakai, Uganda, 2001-2013.

Stephanie Ann Grilo, Xiaoyu Song, Tom Lutalo, Margo Mullinax, Sanyukta Mathur, John Santelli

Open access · goldAbstract read
In one paragraph

Article in BMC women's health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Stephanie Ann GriloDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, 722 W 168th Street, New York, NY, 10032, USA. sag2179@cumc.columbia.edu.
Xiaoyu SongHeilbrunn Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, NY, USA.
Tom LutaloRakai Health Sciences Program, Kalisizo, Uganda.
Margo MullinaxAmerican Jewish World Service, New York, NY, USA.
Sanyukta MathurPopulation Council, Washington, DC, USA.
John SantelliHeilbrunn Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, NY, USA.
Columbia University · USAmerican Jewish World Service · USPopulation Council · USRakai Health Sciences Program · UG

Funding

Rakai Adolescent Project (RAP)R01HD061092 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SANTELLI, JOHN S. · 2009 to 2013
$2.3M
Prevention and Planning LinkagesR01HD072695 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SANTELLI, JOHN S. · 2012 to 2016
$2.2M
National Institute of Child Health and Human Development 1 RO1 Hd072595-01NICHD NIH HHS R01 HD061092NICHD NIH HHS R01 HD072695
6 · The paper itself

Abstract

backgroundUnintended pregnancy is a persistent and global issue with consequences for the health and well-being of mothers and babies. The aim of this paper is to examine unintended pregnancy over time in the context of substantial human immunodeficiency virus (HIV) prevalence and increasing access to anti-retro viral therapy (ART).

methodData are from the Rakai Community Cohort Study (RCCS) - a cohort of communities with 10,000-12,000 adults, ages 15-49, in Rakai District, Uganda. We examined prevalence of current pregnancies over time, intended pregnancy, and unintended pregnancies (unwanted, mistimed, ambivalent). We then examined risk factors for the different categories of unintended pregnancy among women who were currently pregnant. The full sample included 32,205 observations over 13 years.

resultsThe prevalence of mistimed pregnancy and unwanted pregnancy both decreased significantly over time (p < .001). The prevalence of current pregnancies and intended pregnancy showed no significant changes over the thirteen year period. The same overall pattern was found when only examining HIV positive women in the sample; however, the trends were not significant. Out of the 2820 current pregnancies reported, 54.4% were intended, 29.8% were mistimed, 13.2% were unwanted, and 2.5% were ambivalent. After controlling for other predictors, HIV status had no independent effect on mistimed pregnancy but had a significant effect on unwanted pregnancy (RRR = 2.44, 95% CI = 1.65-3.61, p < .001] and ambivalent pregnancy [RRR = 2.07; CI: 1.03 to 4.18, p = 0.041]. In 2004, after the introduction of ART, there was a decreased risk in unintended pregnancy [RR = 0.75; CI: 0.66 to 0.84, p < .001]. Women with a secondary education or higher also had a decreased risk in unintended pregnancy [RR = 0.70; CI: 0.70 to 0.92, p = 0.002]. DISCUSSION: HIV was an important predictor of unwanted pregnancy. Unintended pregnancy decreased in the sample over time which may be due to an increase in ART availability and rising levels of education.

Indexed as

AdolescentAdultCohort StudiesCross-Sectional StudiesFemaleHIV InfectionsHIV SeropositivityHumansMaternal BehaviorMiddle AgedMothersPregnancyPregnancy, UnplannedPregnancy, UnwantedRisk FactorsUgandaHIV/AIDSUnintended pregnancy

Identifiers

PMID29486752
PMCPMC6389071
OpenAlexW2790690429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.