Evidence map›Paper›PMID 29486582›Full record

ArticleAIDS research and human retroviruses2018

Short Communication: Apoptotic Membrane Microparticles Quantified by Fluorescent Bead-Based Assay Are Elevated in HIV and SIV Infections.

Estelle Autissier, Haiying Li, Paul A Goepfert, R Keith Reeves

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Apoptotic extracellular vesicles: unveiling mechanisms, diverse functions, and biomedical implications.Apoptosis : an international journal on programmed cell death · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Estelle Autissier1 Division of Immunology, New England Primate Research Center , Harvard Medical School, Southborough, Massachusetts.
Haiying Li2 Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center , Harvard Medical School, Boston, Massachusetts.
Paul A Goepfert3 Department of Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
R Keith Reeves1 Division of Immunology, New England Primate Research Center , Harvard Medical School, Southborough, Massachusetts.
Beth Israel Deaconess Medical Center · USHarvard University · USRagon Institute of MGH, MIT and Harvard · USUniversity of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Microbial and innate immune mechanisms of oral inflammation during SIV infectionR01DE026327 · NIDCR · DUKE UNIVERSITY · PI REEVES, ROGER KEITH · 2016 to 2020
$3.9M
Antigen-Specific NK Cell Memory Against SIV and HIV VaccinesR01AI120828 · NIAID · DUKE UNIVERSITY · PI REEVES, ROGER KEITH · 2017 to 2020
$3.5M
NCI NIH HHS P30 CA013148NIAID NIH HHS R01 AI120828NIDCR NIH HHS R01 DE026327
6 · The paper itself

Abstract

Apoptotic membrane microparticles (MMPs) derived from dying cells of multiple cell origins are highly immunostimulatory and are indicative of global immune activation and cell death in a variety of diseases. In this study, we developed a flow cytometric bead assay to quantify annexin-V

Indexed as

ApoptosisCell-Derived MicroparticlesAdultAnimalsFemaleFlow CytometryFluorometryHIV InfectionsHumansMacaca mulattaMaleMiddle AgedPlasmaSimian Acquired Immunodeficiency Syndromeexosomesfluorescent beadsHIVmembrane microparticlesSIV

Identifiers

PMID29486582
PMCPMC5934972
OpenAlexW2789472653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.