ArticleAmerican journal of perinatology2018
Physiological Approach to Sodium Supplementation in Preterm Infants.
Article in American journal of perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03889197 (Physiologic Approach to Sodium Supplementation in Premature Infants), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physiologic Approach to Sodium Supplementation in Premature Infants
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sodium supplementation strategies in preterm infants: effects on growth, electrolyte balance, and exploratory evidence on neurodevelopment - a systematic review and meta-analysis.BMC nutrition · 2026Pooled it
- Epidemiology of early onset hyponatremia in extremely preterm neonates: A retrospective observational study.Journal of neonatal-perinatal medicine · 2026Observational
- Nutritional management at 22-23 weeks gestational age: evidence and knowledge gaps.Pediatric research · 2026Review
- Maternal low sodium intake and early postnatal diuretics program metabolic and ventilatory dysfunction in mice.Pediatric research · 2026Article
- Early postnatal nutrition and renal consequences in preterm infants.Pediatric research · 2026Review
- The Changing Landscape of Sodium Needs in the Preterm Neonate for Optimizing Growth and Development.Nutrients · 2026Review
- Sodium Supplementation Algorithm to Promote Growth in Infants Who Are Preterm: Randomized Clinical Trial.Pediatrics open science · 2026Article
- Article
- It's the little things. A framework and guidance for programs to care for infants 22-23 weeks' gestational age.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- A pinch of salt to enhance preemie growth?Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Somatic growth outcomes in response to an individualized neonatal sodium supplementation protocol.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Early-life sodium restriction programs autonomic dysfunction and salt sensitivity in male C57BL/6J mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Oral sodium supplementation on growth and hypertension in preterm infants: an observational cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2024Observational
- Somatic growth outcomes in response to an individualized neonatal sodium supplementation protocol.Research square · 2024Article
- Early-life sodium deprivation programs long-term changes in ingestive behaviors and energy expenditure in C57BL/6J mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- Sodium and Growth in Preterm Infants: A Review.Newborn (Clarksville, Md.) · 2023Article
- Maturational changes in sodium metabolism in periviable infants.Pediatric nephrology (Berlin, Germany) · 2021Observational
- Dissociable effects of dietary sodium in early life upon somatic growth, fluid homeostasis, and spatial memory in mice of both sexes.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Variation in Neonatal Nutrition Practice and Implications: A Survey of Australia and New Zealand Neonatal Units.Frontiers in nutrition · 2021Article
- Fetal storage of osmotically inactive sodium.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveTo implement and evaluate a clinical practice algorithm to identify preterm infants with sodium deficiency and guide sodium supplementation based on urine sodium concentrations. STUDY
designUrine sodium concentration was measured in infants born at 26
resultsData were compared for 50 infants in the 2014-2015 cohort and 40 infants in the 2016 cohort. Urine sodium concentration met criteria for supplementation in 75% of the 2016 cohort infants within the first 4 weeks after birth. Average daily sodium intake was greater in the 2016 cohort compared with the 2014-2015 cohort (
conclusionInstitution of a clinical practice algorithm to instruct clinicians on sodium supplementation in preterm infants may improve growth outcomes.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.