SynthesisPloS one2018
Effects of physical exercise programs on cognitive function in Parkinson's disease patients: A systematic review of randomized controlled trials of the last 10 years.
Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- A Systematic review and meta-analysis on prospective memory rehabilitation in adults with non-progressive acquired brain injury.Scientific reports · 2026Pooled it
- Cost-Effectiveness Analyses of Non-Pharmacological and Non-Surgical Interventions in Idiopathic Parkinson's Disease: A Systematic Review.Journal of Parkinson's disease · 2024Pooled it
- Physical exercise and its effects on people with Parkinson's disease: Umbrella review.PloS one · 2023Pooled it
- Effects of Exercise on Parkinson's Disease: A Meta-Analysis of Brain Imaging Studies.Frontiers in human neuroscience · 2022Pooled it
- Effects of Training with Different Modes of Strength Intervention on Psychosocial Disorders in Adolescents: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Physical exercise improves quality of life, depressive symptoms, and cognition across chronic brain disorders: a transdiagnostic systematic review and meta-analysis of randomized controlled trials.Journal of neurology · 2021Pooled it
- Dance intervention effects on physical function in healthy older adults: a systematic review and meta-analysis.Aging clinical and experimental research · 2021Pooled it
- Telerehabilitation for early-stage Parkinson's disease: A randomized controlled feasibility trial of individualised real-time physiotherapy delivered via a videoconference platform.Journal of Parkinson's disease · 2026Trial
- Feasibility and acceptability of PDConnect, a multi-component intervention to support physical activity in people with Parkinson's disease: A mixed methods study.Journal of Parkinson's disease · 2025Trial
- A digital health home intervention for people within the Alzheimer's disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial.Annals of medicine · 2023Trial
- Cognitively Challenging Agility Boot Camp Program for Freezing of Gait in Parkinson Disease.Neurorehabilitation and neural repair · 2020Trial
- Retinal neurovascular signatures in response to 6-month yoga exercise in patients with Parkinson's Disease.Parkinsonism & related disorders · 2026Article
- Mindfulness combined with cognitive motor dual task training in Parkinson's disease with mild cognitive impairment.iScience · 2026Article
- Structural and functional brain changes following diverse exercise interventions in Parkinson's disease: an MRI-based narrative review.Physical activity and nutrition · 2026Article
- Brain markers of cognitive-motor control of gait function in Parkinson's disease: links with physical activity and aerobic fitness.Physical activity and nutrition · 2026Article
- Effects of physical exercise on cognitive impairment in patients with Alzheimer's disease, Parkinson's disease or mild cognitive impairment: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Review
- Is physical fitness associated with brain structure and function in Parkinson's disease?Brain imaging and behavior · 2026Article
- A Holistic Wellness Prescription for Parkinson's Disease: Evidence-Based Perspectives and Unmet Needs.Movement disorders clinical practice · 2026Review
- Cognitive and Motor Improvements Correlated with Sleep and Activity Following Community-Based Non-contact Boxing in Patients with Parkinson Disease.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- Does cognition affect supervised and unsupervised mobility differently in people with Parkinson's disease? A cross-sectional study.Journal of neuroengineering and rehabilitation · 2026Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the relative importance of cognitive impairment, there was considerable interest in identifying the cognitive profile of PD patients, in order to ensure specific and appropriate therapeutic interventions. PURPOSE: To determine the effects of physical exercise programs on cognitive function in PD patients, compared with the control group. DATA SOURCES: Medline, Cochrane, Scopus, PEDro and Web of Science (last searched in September 2016). STUDY SELECTION: Randomized clinical trials examining the effects of physical exercise programs and cognitive function in PD patients. Nine studies fulfilled the selection criteria and were included in this review. DATA EXTRACTION: Characteristics of the publication, characteristics of the participants, test used for cognitive screening, cognitive domain assessed, tools used to assess cognitive function, characteristics of the experimental intervention, characteristics of the control group, mean results and standard deviation of function cognitive. The PEDro score was used to evaluate methodological quality. DATA SYNTHESIS: Most eligible studies showed good methodological quality based on the PEDro scale. Studies have shown that adapted tango for PD patients, cognitive training combined with motor training, and treadmill training promote the preservation or improvement of cognitive function in PD patients. LIMITATIONS: The diversity of cognitive tests used to assess cognitive function and the high heterogeneity identified between the physical exercise programs.
conclusionsPhysical exercise programs promote positive and significant effects on global cognitive function, processing speed, sustained attention and mental flexibility in PD patients, at a mild to moderate stage for patients with a 6-year clinical diagnosis of PD. However, treadmill training performed 3 times a week for about 60 minutes and for a period of 24 weeks produced larger improvements in cognition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.