Evidence map›Paper›PMID 29485988›Full record

Observational studyPloS one2018

Effectiveness of integrated care including therapeutic assertive community treatment in severe schizophrenia-spectrum and bipolar I disorders: Four-year follow-up of the ACCESS II study.

Daniel Schöttle, Benno G Schimmelmann, Friederike Ruppelt, Alexandra Bussopulos, Marietta Frieling, Evangelia Nika, Luise Antonia Nawara, Dietmar Golks, Andrea Kerstan, Matthias Lange and 15 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01888627 (Integrated Care in Patients With a Psychotic Disorder Fulfilling Definition of Severe Mental Illness), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01888627 naunknown statusnot on this map

Integrated Care in Patients With a Psychotic Disorder Fulfilling Definition of Severe Mental Illness (ACCESS-II Study)

TypeinterventionalSponsorUniversitätsklinikum Hamburg-EppendorfRan2007 to 2025Enrolled400ConditionsSchizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Delusional DisorderArmsIntegrated care
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Mediators of quality of life change in people with severe psychotic disorders treated in integrated care: ACCESS II study.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Article
  12. The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Daniel SchöttlePsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-8589-727X
Benno G SchimmelmannUniversity Hospital of Child and Adolescent Psychiatry, University of Bern, Bern, Switzerland.
Friederike RuppeltPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Alexandra BussopulosPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marietta FrielingPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Evangelia NikaPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Luise Antonia NawaraPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Dietmar GolksPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Andrea KerstanPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Matthias LangePsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Michael SchödlbauerPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anne DaubmannDepartment of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Karl WegscheiderDepartment of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anja RohenkohlPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gizem SarikayaPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mary SenguttaPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Daniel LuedeckePsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Linus WittmannPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gunda OhmStrategic University Development Centre, University Medical Centre, Hamburg-Eppendorf, Hamburg, Germany.
Christina Meigel-SchleiffDepartment of Psychiatry and Psychotherapy, University Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jürgen GallinatDepartment of Psychiatry and Psychotherapy, University Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Klaus WiedemannPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Thomas BockPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anne KarowPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin LambertPsychosis Centre, Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ACCESS-model offers integrated care including assertive community treatment to patients with psychotic disorders. ACCESS proved more effective compared to standard care (ACCESS-I study) and was successfully implemented into clinical routine (ACCESS-II study). In this article, we report the 4-year outcomes of the ACCESS-II study. Between May 2007 and December 2013, 115 patients received continuous ACCESS-care. We hypothesized that the low 2-year disengagement and hospitalization rates and significant improvements in psychopathology, functioning, and quality of life could be sustained over 4 years. Over 4 years, only 10 patients disengaged from ACCESS. Another 23 left for practical reasons and were successfully transferred to other services. Hospitalization rates remained low (13.0% in year 3; 9.1% in year 4). Involuntary admissions decreased from 35% in the 2 years prior to ACCESS to 8% over 4 years in ACCESS. Outpatient contacts remained stably high at 2.0-2.4 per week. We detected significant improvements in psychopathology (effect size d = 0.79), illness severity (d = 1.29), level of functioning (d = 0.77), quality of life (d = 0.47) and stably high client satisfaction (d = 0.02) over 4 years. Most positive effects were observed within the first 2 years with the exception of illness severity, which further improved from year 2 to 4. Within continuous intensive 4-year ACCESS-care, sustained improvements in psychopathology, functioning, quality of life, low service disengagement and re-hospitalization rates, as well as low rates of involuntary treatment, were observed in contrast to other studies, which reported a decline in these parameters once a specific treatment model was stopped. Yet, stronger evidence to prove these results is required.

trial registrationClinical Trial Registration Number: NCT01888627.

Indexed as

Community Mental Health ServicesDelivery of Health Care, IntegratedAdultAmbulatory CareBipolar DisorderFemaleFollow-Up StudiesHospitalizationHumansInvoluntary TreatmentMalePatient DropoutsPatient SatisfactionPsychotic DisordersQuality of LifeSchizophrenia

Identifiers

PMID29485988
PMCPMC5828355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.