Evidence map›Paper›PMID 29485983›Full record

ArticlePLoS biology2018

Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research.

Weng Khong Lim, Sonia Davila, Jing Xian Teo, Chengxi Yang, Chee Jian Pua, Christopher Blöcker, Jing Quan Lim, Jianhong Ching, Jonathan Jiunn Liang Yap, Swee Yaw Tan and 7 more

Open access · goldAbstract read
In one paragraph

Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  9. Multi-Omics Profiling for Health.Molecular & cellular proteomics : MCP · 2023
    Review
  10. An interactive fitness-for-use data completeness tool to assess activity tracker data.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Weng Khong LimSingHealth Duke-NUS Institute of Precision Medicine, Singapore.ORCID 0000-0003-4391-1130
Sonia DavilaSingHealth Duke-NUS Institute of Precision Medicine, Singapore.
Jing Xian TeoSingHealth Duke-NUS Institute of Precision Medicine, Singapore.
Chengxi YangNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.
Chee Jian PuaNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.
Christopher BlöckerCancer and Stem Biology Program, Duke-NUS Medical School, Singapore.
Jing Quan LimLymphoma Genomic Translational Laboratory, Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Jianhong ChingCardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore.
Jonathan Jiunn Liang YapDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Swee Yaw TanDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Anders SahlénDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Calvin Woon-Loong ChinDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Bin Tean TehSingHealth Duke-NUS Institute of Precision Medicine, Singapore.
Steven G RozenSingHealth Duke-NUS Institute of Precision Medicine, Singapore.
Stuart Alexander CookSingHealth Duke-NUS Institute of Precision Medicine, Singapore.
Khung Keong YeoDepartment of Cardiology, National Heart Centre Singapore, Singapore.
Patrick TanSingHealth Duke-NUS Institute of Precision Medicine, Singapore.
National Heart Centre Singapore · SGSingHealth · SGAgency for Science, Technology and Research · SGDuke-NUS Medical School · SGNational Cancer Centre Singapore · SG

Funding

Medical Research Council MC_U120085815
6 · The paper itself

Abstract

The use of consumer-grade wearables for purposes beyond fitness tracking has not been comprehensively explored. We generated and analyzed multidimensional data from 233 normal volunteers, integrating wearable data, lifestyle questionnaires, cardiac imaging, sphingolipid profiling, and multiple clinical-grade cardiovascular and metabolic disease markers. We show that subjects can be stratified into distinct clusters based on daily activity patterns and that these clusters are marked by distinct demographic and behavioral patterns. While resting heart rates (RHRs) performed better than step counts in being associated with cardiovascular and metabolic disease markers, step counts identified relationships between physical activity and cardiac remodeling, suggesting that wearable data may play a role in reducing overdiagnosis of cardiac hypertrophy or dilatation in active individuals. Wearable-derived activity levels can be used to identify known and novel activity-modulated sphingolipids that are in turn associated with insulin sensitivity. Our findings demonstrate the potential for wearables in biomedical research and personalized health.

Indexed as

Cardiovascular Physiological PhenomenaFitness TrackersAdultCardiomegalyExerciseFemaleHealthy VolunteersHeart RateHumansInsulin ResistanceLife StyleMaleMedical OveruseMiddle AgedSphingolipidsSurveys and QuestionnairesSphingolipids

Identifiers

PMID29485983
PMCPMC5828350
OpenAlexW2787945643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.