Evidence map›Paper›PMID 29485622›Full record

ArticleScientific data2018

ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.

Sanchita Bhattacharya, Patrick Dunn, Cristel G Thomas, Barry Smith, Henry Schaefer, Jieming Chen, Zicheng Hu, Kelly A Zalocusky, Ravi D Shankar, Shai S Shen-Orr and 3 more

Abstract read
In one paragraph

Article in Scientific data, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 519 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
519citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

519 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  10. bioRxiv : the preprint server for biology · 2026
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  20. VO: The Vaccine Ontology.Scientific data · 2026
    Article

459 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sanchita BhattacharyaInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.ORCID 0000-0002-3056-0733
Patrick DunnNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.ORCID 0000-0003-1868-9689
Cristel G ThomasNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Barry SmithDepartment of Philosophy, University at Buffalo, Buffalo, NY 14260, USA.
Henry SchaeferEnterprise Science and Computing Inc., Rockville, MD 20850, USA.
Jieming ChenInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.
Zicheng HuInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.
Kelly A ZalocuskyInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.
Ravi D ShankarDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Shai S Shen-OrrDepartment of Immunology, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
Elizabeth ThomsonNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.ORCID 0000-0002-1267-6062
Jeffrey WiserNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Atul J ButteInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.ORCID 0000-0002-7433-2740

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
PRO: A Protein Ontology in Open Biomedical OntologiesR01GM080646 · NIGMS · UNIVERSITY OF DELAWARE · PI WU, CATHY H. · 2007 to 2018
$8.9M
NCATS NIH HHS UL1 TR001412NIAID NIH HHS HHSN272201200028CNIGMS NIH HHS R01 GM080646
6 · The paper itself

Abstract

Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components-Private Data, Shared Data, Data Analysis, and Resources-for data archiving, dissemination, analyses, and reuse. To date, more than 300 studies have been made freely available through the Shared Data portal (www.immport.org/immport-open), which allows research data to be repurposed to accelerate the translation of new insights into discoveries.

Indexed as

Allergy and ImmunologyBiological AssayDatasets as TopicTranslational Research, BiomedicalAccess to InformationReproducibility of Results

Identifiers

PMID29485622
PMCPMC5827693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.