Evidence map›Paper›PMID 29485195›Full record

ArticleImmunology2018

Characterization of genetic predisposition and autoantibody profile in atypical haemolytic-uraemic syndrome.

Bahadur Singh Gurjar, Tholu Manikanta Sriharsha, Angika Bhasym, Savit Prabhu, Mamta Puraswani, Priyanka Khandelwal, Himanshi Saini, Savita Saini, Anita Kamra Verma, Priyadarshini Chatterjee and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 1 country.

Bahadur Singh GurjarNational Institute of Immunology, New Delhi, India.
Tholu Manikanta SriharshaNational Centre for Cell Science, S. P. Pune University Campus, Pune, India.
Angika BhasymRegional Centre for Biotechnology, Faridabad, India.
Savit PrabhuPaediatric Biology Centre, Translational Health Science and Technology Institute, Faridabad, India.
Mamta PuraswaniDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Priyanka KhandelwalDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Himanshi SainiDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Savita SainiDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Anita Kamra VermaKirori Mal College, University of Delhi, Delhi, India.
Priyadarshini ChatterjeeRegional Centre for Biotechnology, Faridabad, India.
Prasenjit GuchhaitRegional Centre for Biotechnology, Faridabad, India.
Vineeta BalNational Institute of Immunology, New Delhi, India.
Anna GeorgeNational Institute of Immunology, New Delhi, India.ORCID http://orcid.org/0000-0001-9401-0944
Satyajit RathNational Institute of Immunology, New Delhi, India.ORCID http://orcid.org/0000-0002-7343-1173
Arvind SahuNational Centre for Cell Science, S. P. Pune University Campus, Pune, India.
Amita SharmaDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Pankaj HariDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Aditi SinhaDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Arvind BaggaDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · INNational Centre for Cell Science · INNational Institute of Immunology · INRegional Centre for Biotechnology · INTranslational Health Science and Technology Institute · INAgharkar Research Institute · INManipal Academy of Higher Education · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that Indian paediatric patients with atypical haemolytic-uraemic syndrome (aHUS) showed high frequencies of anti-complement factor H (FH) autoantibodies that are correlated with homozygous deletion of the genes for FH-related proteins 1 and 3 (FHR1 and FHR3) (FHR1/3

Indexed as

complement factor H autoantibodiesgenetic predisposition to autoimmunityhaemolytic-uraemic syndrome

Identifiers

PMID29485195
PMCPMC6050217
OpenAlexW2793354308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.