ReviewInternational journal of radiation oncology, biology, physics2018
Decision-Making Strategy for Rectal Cancer Management Using Radiation Therapy for Elderly or Comorbid Patients.
Review in International journal of radiation oncology, biology, physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Preoperative chemoradiotherapy in older patients with rectal cancer guided by comprehensive geriatric assessment within a multidisciplinary team-a multicenter phase II trial.BMC geriatrics · 2024Trial
- Changing patterns of colorectal cancer in China between 2000 and 2016 based on tertiary hospital data.Discover oncology · 2025Article
- Neoadjuvant treatment of rectal cancer: Where we are and where we are going.World journal of clinical oncology · 2024Article
- Elderly Rectal Cancer: An Updated Review.Current oncology reports · 2024Review
- Planned organ preservation for elderly patients with rectal cancer using short course radiotherapy and a contact brachytherapy boost-an International multi-institution analysis.Clinical and translational radiation oncology · 2023Article
- Geriatric Radiation Oncology: What We Know and What Can We Do Better?Clinical interventions in aging · 2023Review
- Image-guided high-dose-rate brachytherapy for rectal cancer: technical note and first clinical experience on an organ-preserving approach.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Article
- Review
- The association of age with acute toxicities in NRG oncology combined modality lower GI cancer trials.Journal of geriatric oncology · 2022Article
- Baseline anaemia increases locally advanced rectal cancer mortality in older patients undergoing preoperative chemoradiation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Developing an electronic geriatric assessment to improve care of older adults with cancer receiving radiotherapy.Technical innovations & patient support in radiation oncology · 2020Article
- Toxicity and outcomes in older versus younger patients treated with trimodality therapy for locally advanced rectal cancer.Journal of geriatric oncology · 2020Article
- Recommendations on Management of Locally Advanced Rectal Cancer During the COVID-19 Pandemic: an Iranian Consensus.Journal of gastrointestinal cancer · 2020Review
- Watch and wait approach in rectal cancer: Current controversies and future directions.World journal of gastroenterology · 2020Review
- Aberrant Expression of RAD52, Its Prognostic Impact in Rectal Cancer and Association with Poor Survival of Patients.International journal of molecular sciences · 2020Article
- Improving quality of care and clinical outcomes for rectal cancer through clinical audits in a multicentre cancer care organisation.Radiation oncology (London, England) · 2020Article
- Locally Advanced Rectal Cancer: Treatment Approach in Elderly Patients.Current treatment options in oncology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Rectal cancer predominantly affects patients older than 70 years, with peak incidence at age 80 to 85 years. However, the standard treatment paradigm for rectal cancer oftentimes cannot be feasibly applied to these patients owing to frailty or comorbid conditions. There are currently little information and no treatment guidelines to help direct therapy for patients who are elderly and/or have significant comorbidities, because most are not included or specifically studied in clinical trials. More recently various alternative treatment options have been brought to light that may potentially be utilized in this group of patients. This critical review examines the available literature on alternative therapies for rectal cancer and proposes a treatment algorithm to help guide clinicians in treatment decision making for elderly and comorbid patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.