Evidence map›Paper›PMID 29484973›Full record

ReviewCurrent medicinal chemistry2019

Organic Fluorescent Dye-based Nanomaterials: Advances in the Rational Design for Imaging and Sensing Applications.

Denis Svechkarev, Aaron M Mohs

Open access · greenAbstract readReview
In one paragraph

Review in Current medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 85 citations in OpenAlex.

  1. Review
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  8. Machine learning assisted identification of antibiotic-resistantMicrochemical journal : devoted to the application of microtechniques in all branches of science · 2024
    Article
  9. Article
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  11. Review
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  13. In Vivo Fluorescence Molecular Imaging Using Covalent Organic Nanosheets Without Labeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Denis SvechkarevUniversity of Nebraska Medical Center, Department of Pharmaceutical Sciences, Fred and Pamela Buffett Cancer Center, Omaha, NE, United States.
Aaron M MohsUniversity of Nebraska Medical Center, Department of Pharmaceutical Sciences, Fred and Pamela Buffett Cancer Center, Omaha, NE, United States.
University of Nebraska Medical Center · US

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
Tunable Fluorescent Organic Nanoparticles for Cancer Imaging ApplicationsR21CA212500 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MOHS, AARON M. · 2017 to 2019
$596k
NCI NIH HHS P30 CA036727NCI NIH HHS R21 CA212500
6 · The paper itself

Abstract

Self-assembled fluorescent nanomaterials based on small-molecule organic dyes are gaining increasing popularity in imaging and sensing applications over the past decade. This is primarily due to their ability to combine spectral properties tunability and biocompatibility of small molecule organic fluorophores with brightness, chemical and colloidal stability of inorganic materials. Such a unique combination of features comes with rich versatility of dye-based nanomaterials: from aggregates of small molecules to sophisticated core-shell nanoarchitectures involving hyperbranched polymers. Along with the ongoing discovery of new materials and better ways of their synthesis, it is very important to continue systematic studies of fundamental factors that regulate the key properties of fluorescent nanomaterials: their size, polydispersity, colloidal stability, chemical stability, absorption and emission maxima, biocompatibility, and interactions with biological interfaces. In this review, we focus on the systematic description of various types of organic fluorescent nanomaterials, approaches to their synthesis, and ways to optimize and control their characteristics. The discussion is built on examples from reports on recent advances in the design and applications of such materials. Conclusions made from this analysis allow a perspective on future development of fluorescent nanomaterials design for biomedical and related applications.

Indexed as

Fluorescent DyesMolecular ConformationNanostructuresOptical ImagingOrganic ChemicalsSmall Molecule LibrariesFluorescent DyesOrganic ChemicalsSmall Molecule Librariescolloidal stabilitymolecular designnanomaterial synthesisOrganic fluorophorespolymeric aggregatesspectral propertiesstructure-property relationshipsupramolecular assembly.

Identifiers

PMID29484973
PMCPMC6703954
OpenAlexW2792997298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.