ArticleJournal of biophotonics2018
Pain management using photobiomodulation: Mechanisms, location, and repeatability quantified by pain threshold and neural biomarkers in mice.
Article in Journal of biophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- The Role of Photobiomodulation to Modulate Ion Channels in the Nervous System: A Systematic Review.Cellular and molecular neurobiology · 2024Pooled it
- Devices used for photobiomodulation of the brain-a comprehensive and systematic review.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Clinical and radiographic efficacy of photobiomodulation, platelet-rich fibrin, and their combination for socket preservation: a randomized clinical trial.BMC oral health · 2026Trial
- Photobiomodulation therapy (red/NIR LEDs) reduced the length of stay in intensive care unit and improved muscle function: A randomized, triple-blind, and sham-controlled trial.Journal of biophotonics · 2024Trial
- Photobiomodulation for Managing "Dry Socket": A Randomised Controlled Trial.International dental journal · 2023Trial
- Evaluation of the effects of photobiomodulation with different laser application doses on injection pain in children: a randomized clinical trial.Lasers in medical science · 2022Trial
- Acute effect of photobiomodulation using light-emitting diodes (LEDs) on baroreflex sensitivity during and after constant loading exercise in patients with type 2 diabetes mellitus.Lasers in medical science · 2020Trial
- A Translational Review of Mechanisms of Effectiveness of Photobiomodulation on Somatosensory Neurons and the Peripheral Nervous System-From Molecular Mechanisms to Clinical Applications in Medicine and Dentistry.Current issues in molecular biology · 2026Review
- Effects of Phototherapy on Sleep, Fatigue and Quality of Life in Dermatology Patients: A Pilot Study.Sisli Etfal Hastanesi tip bulteni · 2026Article
- Combined aerobic exercise and photobiomodulation for pain and other symptoms in fibromyalgia: study protocol.Pain management · 2025Article
- The Effects of High-Power Laser Therapy on the Treatment of Patients with Myofascial Trigger Points in the Upper Trapezius Muscle: A Randomized Controlled Trial.Journal of lasers in medical sciences · 2025Article
- Photobiomodulation therapy.JADA foundational science · 2025Review
- Photobiomodulation: shining a light on depression.Theranostics · 2025Review
- Direct Photobiomodulation Therapy on the Sciatic Nerve Significantly Attenuates Acute Nociceptive Sensitivity Without Affecting Motor Output.Neuromodulation : journal of the International Neuromodulation Society · 2024Article
- Photobiomodulation as a Potential Therapy for Erectile Function: A Preclinical Study in a Cavernous Nerve Injury Model.The world journal of men's health · 2024Article
- Light Therapy in Chronic Migraine.Current pain and headache reports · 2024Review
- Photobiomodulation for pain relief: Model-based estimates of effective doses of light at the neural target.Journal of photochemistry and photobiology. B, Biology · 2024Article
- Selective neural inhibition via photobiomodulation alleviates behavioral hypersensitivity associated with small sensory fiber activation.Lasers in surgery and medicine · 2024Article
- Effects of intravascular photobiomodulation on cognitive impairment and crossed cerebellar diaschisis in patients with traumatic brain injury: a longitudinal study.Lasers in medical science · 2023Article
- Near-Infrared Photobiomodulation of the Peripheral Nerve Inhibits the Neuronal Firing in a Rat Spinal Dorsal Horn Evoked by Mechanical Stimulation.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Photobiomodulation (PBM) is a simple, efficient and cost-effective treatment for both acute and chronic pain. We previously showed that PBM applied to the mouse head inhibited nociception in the foot. Nevertheless, the optimum parameters, location for irradiation, duration of the effect and the mechanisms of action remain unclear. In the present study, the pain threshold in the right hind paw of mice was studied, after PBM (810 nm CW laser, spot size 1 or 6 cm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.