Evidence map›Paper›PMID 29484802›Full record

ArticleThe international journal of medical robotics + computer assisted surgery : MRCAS2018

System and path planning algorithm for low-kV X-ray free-form surface irradiation.

Andreas Rothfuss, Oliver Oesterle, Daniel Bürgy, Charles Nwankwo, Frank Schneider, Auguste van Poelgeest, Frederik Wenz, Jan Stallkamp, Sven Clausen

Abstract read
In one paragraph

Article in The international journal of medical robotics + computer assisted surgery : MRCAS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. System and path planning algorithm for low-kV X-ray free-form surface irradiation.The international journal of medical robotics + computer assisted surgery : MRCAS · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andreas RothfussProject group for Automation in Medicine and Biotechnology, Fraunhofer IPA, Mannheim, Germany.ORCID http://orcid.org/0000-0002-7323-6861
Oliver OesterleProject group for Automation in Medicine and Biotechnology, Fraunhofer IPA, Mannheim, Germany.
Daniel BürgyDepartment of Radiotherapy and Radiation Oncology, Medical Faculty Mannheim at Heidelberg University, Mannheim, Germany.
Charles NwankwoDepartment of Radiotherapy and Radiation Oncology, Medical Faculty Mannheim at Heidelberg University, Mannheim, Germany.
Frank SchneiderDepartment of Radiotherapy and Radiation Oncology, Medical Faculty Mannheim at Heidelberg University, Mannheim, Germany.
Auguste van PoelgeestProject group for Automation in Medicine and Biotechnology, Fraunhofer IPA, Mannheim, Germany.
Frederik WenzDepartment of Radiotherapy and Radiation Oncology, Medical Faculty Mannheim at Heidelberg University, Mannheim, Germany.
Jan StallkampProject group for Automation in Medicine and Biotechnology, Fraunhofer IPA, Mannheim, Germany.
Sven ClausenDepartment of Radiotherapy and Radiation Oncology, Medical Faculty Mannheim at Heidelberg University, Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIntraoperative radiotherapy (IORT) after surgical resection using a low-kV-X-ray source is a proven method used in cancer treatment. However, the shape and size of the targeted surface area are limited to the size of the available applicators. This can lead to nonconformal and therefore suboptimal treatment for many patients.

methodsA system is proposed comprising an X-ray source with an applicator for surface irradiation mounted on a robotic arm. This is controlled by an algorithm designed for planning the required continuous path, enabling irradiation of any desired shape with a controlled dose distribution.

resultsThe system is shown to be capable of irradiating areas composed of rectangles on a flat surface with a homogeneity index of less than 7% inside the targeted area.

conclusionThe presented results demonstrate the potential of the proposed setup to eliminate the current limitations, leading to better treatment of patients.

Indexed as

AlgorithmsCalibrationHumansNeoplasmsRadiotherapy Planning, Computer-AssistedRoboticsX-Raysbrachytherapycontinuous path planningiortmodelingsimulationx-ray

Identifiers

PMID29484802
PMCPMC5947750

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.