Evidence map›Paper›PMID 29484715›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2018

3D Jet Writing: Functional Microtissues Based on Tessellated Scaffold Architectures.

Jacob H Jordahl, Luis Solorio, Hongli Sun, Stacy Ramcharan, Clark B Teeple, Henry R Haley, Kyung Jin Lee, Thomas W Eyster, Gary D Luker, Paul H Krebsbach and 1 more

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Polymers for Melt Electrowriting.Advanced healthcare materials · 2021
    Review
  15. Article
  16. Advances in Hybrid Fabrication toward Hierarchical Tissue Constructs.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacob H JordahlBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Luis SolorioBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Hongli SunBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Stacy RamcharanBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Clark B TeepleBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Henry R HaleyBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Kyung Jin LeeBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Thomas W EysterBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Gary D LukerBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Paul H KrebsbachBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Joerg LahannBiointerfaces Institute, NCRC B10-A175, 2800 Plymouth Rd, Ann Arbor, MI, 48109, USA.

Funding

Microfluidics in Biomedical Sciences Training ProgramT32EB005582 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FAN, XUDONG · 2005 to 2020
$3.9M
Environmental Regulation of Cancer Stem Cell Plasticity in MetastasisU01CA210152 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LAHANN, JOERG, LUKER, GARY D · 2017 to 2021
$3.6M
Engineering the Cancer MicroenvironmentR00CA198929 · NCI · PURDUE UNIVERSITY · PI SOLORIO, LUIS · 2017 to 2019
$697k
MicroCT 100S10RR026475 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOHN, DAVID H. · 2010 to 2010
$381k
Engineering the Cancer MicroenvironmentK99CA198929 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOLORIO, LUIS · 2016 to 2016
$97k
NCI NIH HHS K99 CA198929NCI NIH HHS R00 CA198929NCI NIH HHS U01 CA210152NCRR NIH HHS S10 RR026475NIBIB NIH HHS T32 EB005582
6 · The paper itself

Abstract

The advent of adaptive manufacturing techniques supports the vision of cell-instructive materials that mimic biological tissues. 3D jet writing, a modified electrospinning process reported herein, yields 3D structures with unprecedented precision and resolution offering customizable pore geometries and scalability to over tens of centimeters. These scaffolds support the 3D expansion and differentiation of human mesenchymal stem cells in vitro. Implantation of these constructs leads to the healing of critical bone defects in vivo without exogenous growth factors. When applied as a metastatic target site in mice, circulating cancer cells home in to the osteogenic environment simulated on 3D jet writing scaffolds, despite implantation in an anatomically abnormal site. Through 3D jet writing, the formation of tessellated microtissues is demonstrated, which serve as a versatile 3D cell culture platform in a range of biomedical applications including regenerative medicine, cancer biology, and stem cell biotechnology.

Indexed as

Printing, Three-DimensionalAnimalsCell DifferentiationHumansMesenchymal Stem CellsMiceOsteogenesisTissue EngineeringTissue ScaffoldsWriting3D cell culturecancerelectrospinningmicrotissuetissue engineering

Identifiers

PMID29484715
PMCPMC6112611

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.