Evidence map›Paper›PMID 29484277›Full record

Review3 Biotech2018

World market and biotechnological production of itaconic acid.

Juliana Cunha da Cruz, Aline Machado de Castro, Eliana Flávia Camporese Sérvulo

Abstract readReview
In one paragraph

Review in 3 Biotech, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Revisiting applications of itaconic acid-based polymers obtained by (poly)condensation chemistry.Green chemistry : an international journal and green chemistry resource : GC · 2026
    Review
  2. Extracellular Phosphate Availability ImpactsJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
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  15. Article
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  17. Microorganisms · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juliana Cunha da Cruz1Escola de Química, Universidade Federal do Rio de Janeiro, 2030, Centro de Tecnologia, Ilha do Fundão, Rio de Janeiro, RJ 21949-909 Brazil.ORCID 0000-0002-4705-9208
Aline Machado de Castro2Divisão de Biotecnologia, Centro de Pesquisa e Desenvolvimento, PETROBRAS, Av. Horácio Macedo, 950. Ilha do Fundão, Rio de Janeiro, RJ 21941-915 Brazil.
Eliana Flávia Camporese Sérvulo1Escola de Química, Universidade Federal do Rio de Janeiro, 2030, Centro de Tecnologia, Ilha do Fundão, Rio de Janeiro, RJ 21949-909 Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The itaconic acid (IA) world market is expected to exceed 216 million of dollars by 2020 as a result of an increasing demand for bio-based chemicals. The potential of this organic acid produced by fermentation mainly with filamentous fungi relies on the vast industrial applications of polymers derived from it. The applications may be as a superabsorbent polymer for personal care or agriculture, unsaturated polyester resin for the transportation industry, poly(methyl methacrylate) for electronic devices, among many others. However, the existence of other substitutes and the high production cost limit the current IA market. IA manufacturing is done mainly in China and other Asia-Pacific countries. Higher economic feasibility and production worldwide may be achieved with the use of low-cost feedstock of local origin and with the development of applications targeted to specific local markets. Moreover, research on the biological pathway for IA synthesis and the effect of medium composition are important for amplifying the knowledge about the production of that biochemical with great market potential.

Indexed as

Bio-based chemicalsBio-based polymersFungal fermentative processesItaconic acidItaconic acid polymersItaconic acid trading marketSustainable materials

Identifiers

PMID29484277
PMCPMC5815973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.