ArticleBrain and behavior2018
Brain resting-state networks in adolescents with high-functioning autism: Analysis of spatial connectivity and temporal neurodynamics.
Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Revolutionizing Pediatric Neurophysiology With Magnetoencephalography.Psychophysiology · 2026Review
- Infants' reorienting efficiency depends on parental autistic traits and predicts future socio-communicative behaviors.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Systematic Bibliometric and Visualized Analysis of Research Hotspots and Trends on Autism Spectrum Disorder Neuroimaging.Disease markers · 2022Article
- Disrupted intra- and inter-network connectivity in unilateral acute tinnitus with hearing loss.Frontiers in aging neuroscience · 2022Article
- Co-activation pattern alterations in autism spectrum disorder-A volume-wise hierarchical clustering fMRI study.Brain and behavior · 2021Article
- Functional Networks Abnormalities in Autism Spectrum Disorder: Age-Related Hypo and Hyper Connectivity.Brain topography · 2021Article
- The Development of Brain Network in Males with Autism Spectrum Disorders from Childhood to Adolescence: Evidence from fNIRS Study.Brain sciences · 2021Article
- Alterations of Prefrontal-Posterior Information Processing Patterns in Autism Spectrum Disorders.Frontiers in neuroscience · 2021Article
- Article
- Autistic traits are associated with the functional connectivity of between-but not within-attention systems in the general population.BMC neuroscience · 2020Article
- Article
- Children With Autism Produce a Unique Pattern of EEG Microstates During an Eyes Closed Resting-State Condition.Frontiers in human neuroscience · 2020Article
- Space-time recurrences for functional connectivity evaluation and feature extraction in motor imagery brain-computer interfaces.Medical & biological engineering & computing · 2019Article
- Altered Functional Connectivity in Children With Low-Function Autism Spectrum Disorders.Frontiers in neuroscience · 2019Article
- Increased scale-free dynamics in salience network in adult high-functioning autism.NeuroImage. Clinical · 2019Article
- Brain resting-state networks in adolescents with high-functioning autism: Analysis of spatial connectivity and temporal neurodynamics.Brain and behavior · 2018Article
Corrections and comments
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Authors and funding
11 authors.
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Abstract
Introduction: Autism spectrum disorder (ASD) is mainly characterized by functional and communication impairments as well as restrictive and repetitive behavior. The leading hypothesis for the neural basis of autism postulates globally abnormal brain connectivity, which can be assessed using functional magnetic resonance imaging (fMRI). Even in the absence of a task, the brain exhibits a high degree of functional connectivity, known as intrinsic, or resting-state, connectivity. Global default connectivity in individuals with autism versus controls is not well characterized, especially for a high-functioning young population. The aim of this study is to test whether high-functioning adolescents with ASD (HFA) have an abnormal resting-state functional connectivity. Materials and Methods: We performed spatial and temporal analyses on resting-state networks (RSNs) in 13 HFA adolescents and 13 IQ- and age-matched controls. For the spatial analysis, we used probabilistic independent component analysis (ICA) and a permutation statistical method to reveal the RSN differences between the groups. For the temporal analysis, we applied Granger causality to find differences in temporal neurodynamics. Results: Controls and HFA display very similar patterns and strengths of resting-state connectivity. We do not find any significant differences between HFA adolescents and controls in the spatial resting-state connectivity. However, in the temporal dynamics of this connectivity, we did find differences in the causal effect properties of RSNs originating in temporal and prefrontal cortices. Conclusion: The results show a difference between HFA and controls in the temporal neurodynamics from the ventral attention network to the salience-executive network: a pathway involving cognitive, executive, and emotion-related cortices. We hypothesized that this weaker dynamic pathway is due to a subtle trigger challenging the cognitive state prior to the resting state.
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