Evidence map›Paper›PMID 29484136›Full record

ArticleOncotarget2018

Jeffrey C Francis, Amy Capper, Jian Ning, Eleanor Knight, Johann de Bono, Amanda Swain

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  10. Sex determining region Y-box 9 induced microtubule formation and epithelial⁃mesenchymal transition in human oral squamous cell carcinoma CAL27 cells.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeffrey C FrancisDivision of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK.
Amy CapperDivision of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK.
Jian NingTumour Profiling Unit, The Institute of Cancer Research, London SW3 6JB, UK.
Eleanor KnightTumour Profiling Unit, The Institute of Cancer Research, London SW3 6JB, UK.
Johann de BonoDivision of Clinical Studies, The Institute of Cancer Research, London SM2 5NG, UK.
Amanda SwainDivision of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK.
Institute of Cancer Research · GB

Funding

Prostate Cancer UK PG13-019
6 · The paper itself

Abstract

Aggressive lethal prostate cancer is characterised by tumour invasion, metastasis and androgen resistance. Understanding the mechanisms by which localised disease progresses to advanced lethal stages is key to the development of effective therapies. Here we have identified a novel role for the transcription factor, SOX9, as a driver of aggressive invasive prostate cancer. Using genetically modified mouse models, we show that increased

Indexed as

aggressive invasive prostate cancercell lineage plasticityepithelial to mesenchymal transitionprostate cancer mouse models

Identifiers

PMID29484136
PMCPMC5800928
OpenAlexW2783064148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.