Evidence map›Paper›PMID 29484021›Full record

ReviewOpen access Macedonian journal of medical sciences2018

Arthrospira Platensis - Potential in Dermatology and Beyond.

Uwe Wollina, Cristiana Voicu, Serena Gianfaldoni, Torello Lotti, Katlein França, Georgi Tchernev

Open access · diamondAbstract readReview
In one paragraph

Review in Open access Macedonian journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Hepatoprotective, anti-inflammatory, and wound healing effects of spirulina in rats.Journal of advanced veterinary and animal research · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Uwe WollinaStädtisches Klinikum Dresden - Department of Dermatology and Allergology, Dresden, Sachsen, Germany.
Cristiana VoicuPolisano Clinic - Department of Dermatology and Venereology, Piscului 16, Corbeanca, Ilfov 077065, Romania.
Serena GianfaldoniUniversity G. Marconi of Rome - Dermatology and Venereology, Rome, Italy.
Torello LottiUniversity G. Marconi of Rome - Dermatology and Venereology, Rome, Italy.
Katlein FrançaDepartment of Dermatology and Cutaneous Surgery, Department of Psychiatry & Behavioral Sciences; Institute for Bioethics and Health Policy, University of Miami Miller School of Medicine, Miami, FL, USA.
Georgi TchernevDepartment of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, Sofia, Bulgaria.
Ministry of Interior · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The search for natural products with benefits for health in general and of potential for treating human disease has gained wider interest world-wide. Here, we analyse current data on the microalga Arthrospira platensis (AP), that has been used in nutrition since ancient times in Fare East and African communities, for medical purposes with a focus on dermatology. Extracts of AP have been investigated in vitro and in vivo. The alga is rich in proteins, lipopolysaccharides and gamma-linolenic acid. AP extracts, phycocyanin compounds and polysaccharide calcium spirulan (Ca-SP) have been evaluated in various models. It could be demonstrated, that AP has significant antioxidant activity, prevents viruses from entry into target cells and inhibits the colonisation of wounds by multi-resistant bacteria. Furthermore, anti-cancer activity was documented in models of oral cancer, melanoma, and UV-induced non-melanoma skin cancer.

Indexed as

Arthrospira platensisCalcium spirulanGamma-linolenic acidMicroalgaePhycocyanin

Identifiers

PMID29484021
PMCPMC5816296
OpenAlexW2782891385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.