Evidence map›Paper›PMID 29483877›Full record

ArticleFrontiers in physiology2018

Participation of Arachidonic Acid Metabolism in the Aortic Aneurysm Formation in Patients with Marfan Syndrome.

María E Soto, Verónica Guarner-Lans, Karla Y Herrera-Morales, Israel Pérez-Torres

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Skeletal muscle alterations in Marfan syndrome: a systematic review.Journal of muscle research and cell motility · 2025
    Pooled it
  2. Downregulation ofMolecular therapy. Nucleic acids · 2026
    Article
  3. Article
  4. Mechanisms of metabolic reprogramming in abdominal aortic aneurysm.Frontiers in cell and developmental biology · 2025
    Review
  5. Progress and perspectives of metabolic biomarkers in human aortic dissection.Metabolomics : Official journal of the Metabolomic Society · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

María E SotoDepartment of Immunology, Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City, Mexico.
Verónica Guarner-LansDepartment of Physiology, Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City, Mexico.
Karla Y Herrera-MoralesCardiothoracic Surgery, Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City, Mexico.
Israel Pérez-TorresDepartment of Pathology, Instituto Nacional de Cardiología "Ignacio Chávez", Mexico City, Mexico.
Instituto Nacional de Cardiología · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marfan syndrome (MFS) is a pleiotropic genetic disease involving the cardiovascular system where a fibrillin-1 mutation is present. This mutation is associated with accelerated activation of transforming growth factor β (TGFβ1) which contributes to the formation of aneurysms in the root of the aorta. There is an imbalance in the synthesis of thromboxane A

Indexed as

aortic aneurysmarachidonic acidcyclooxygenaseinflammationmarfan syndrome

Identifiers

PMID29483877
PMCPMC5816394
OpenAlexW2790356497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.