ReviewLab animal2018
New technologies for developing second generation retinal prostheses.
Review in Lab animal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Restoration of Saccadic Eye Movements and Visually Guided Behavior in Ambient White Light with Photoswitchable Small Molecules.Journal of the American Chemical Society · 2026Article
- Phagocytosis by retinal pigment epithelium and microglia does not affect vision restoration by P3HT nanoparticles in Retinitis pigmentosa.Cell death & disease · 2026Article
- Review
- A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina.Nature communications · 2025Article
- Article
- Investigations on artificially extending the spectral range of natural vision.APL bioengineering · 2023Article
- The p-ERG spatial acuity in the biomedical pig under physiological conditions.Scientific reports · 2022Article
- Retinal Organoids and Retinal Prostheses: An Overview.International journal of molecular sciences · 2022Review
- Vertical-junction photodiodes for smaller pixels in retinal prostheses.Journal of neural engineering · 2021Article
- Subretinally injected semiconducting polymer nanoparticles rescue vision in a rat model of retinal dystrophy.Nature nanotechnology · 2020Article
- Harmonic-balance circuit analysis for electro-neural interfaces.Journal of neural engineering · 2020Article
- Retinal Prosthetic Approaches to Enhance Visual Perception for Blind Patients.Micromachines · 2020Review
- High-Capacity, Fast-Response, and Photocapacitor-Based Terpolymer Phosphor Composite.Polymers · 2020Article
- Biocompatibility of a Conjugated Polymer Retinal Prosthesis in the Domestic Pig.Frontiers in bioengineering and biotechnology · 2020Article
- Editorial: A Conversation With the Brain: Can We Speak Its Language?Frontiers in neuroscience · 2020Article
- Retinal Ganglion Cell Death as a Late Remodeling Effect of Photoreceptor Degeneration.International journal of molecular sciences · 2019Review
- Optoelectronic control of single cells using organic photocapacitors.Science advances · 2019Article
- Retinal remodeling following photoreceptor degeneration causes retinal ganglion cell death.Neural regeneration research · 2018Article
- Photogenerated Electrical Fields for Biomedical Applications.Frontiers in bioengineering and biotechnology · 2018Review
- Advances in retinal prosthesis systems.Therapeutic advances in ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inherited or age-dependent retinal dystrophies such as Retinitis pigmentosa (RP) and macular degeneration (MD) are among the most prevalent causes of blindness. Despite enormous efforts, no established pharmacological treatment to prevent or cure photoreceptor degeneration has been identified. Given the relative survival of the inner retina, attempts have been made to restore vision with optogenetics or with retinal neuroprostheses to allow light-dependent stimulation of the inner retinal network. While microelectrode and photovoltaic devices based on inorganic technologies have been proposed and in many cases implanted in RP patients, a new generation of prosthetics based on organic molecules, such as organic photoswitches and conjugated polymers, is demonstrating an unexpected potential for visual rescue and intimate interactions with functioning tissue. Organic devices are starting a new era of tissue electronics, in which light-sensitive molecules and live tissues integrate and tightly interact, producing a new ecosystem of organic prosthetics and intelligent biotic/abiotic interfaces. In addition to the retina, the applications of these interfaces might be extended in the future to other biomedical fields.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.