Evidence map›Paper›PMID 29483669›Full record

ArticleEuropean journal of human genetics : EJHG2018

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population.

Emil V R Appel, Ida Moltke, Marit E Jørgensen, Peter Bjerregaard, Allan Linneberg, Oluf Pedersen, Anders Albrechtsen, Torben Hansen, Niels Grarup

Open access · bronzeAbstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Emil V R AppelThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark. vincent@sund.ku.dk.ORCID http://orcid.org/0000-0001-7704-6611
Ida MoltkeThe Bioinformatics Centre, Department of Biology, University of Copenhagen, 2200, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-7052-8554
Marit E JørgensenSteno Diabetes Center, 2820, Gentofte, Denmark.
Peter BjerregaardNational Institute of Public Health, University of Southern Denmark, 1353, Copenhagen, Denmark.
Allan LinnebergResearch Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-0994-0184
Oluf PedersenThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Anders AlbrechtsenThe Bioinformatics Centre, Department of Biology, University of Copenhagen, 2200, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-7306-031X
Torben HansenThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Niels GrarupThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5526-1070
University of Copenhagen · DKIlisimatusarfik · GLSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously showed that a common genetic variant leads to a remarkably increased risk of type 2 diabetes (T2D) in the small and historically isolated Greenlandic population. Motivated by this, we aimed at discovering novel genetic determinants for glycated hemoglobin (HbA

Indexed as

Genetic Predisposition to DiseaseAnkyrinsAsian PeopleBlood GlucoseDiabetes Mellitus, Type 2EthnicityFemaleGenetic Association StudiesGenetic VariationGenotypeGerminal Center KinasesGlycated HemoglobinGreenlandHumansInuitMaleANK1 protein, humanAnkyrinsBlood GlucoseGerminal Center KinasesGlycated HemoglobinProtein Serine-Threonine Kinases

Identifiers

PMID29483669
PMCPMC5974304
OpenAlexW2793490584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.