ArticleScientific reports2018
Influent factors of gestational vitamin D deficiency and its relation to an increased risk of preterm delivery in Chinese population.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The effect of vitamin D deficiency during pregnancy on adverse birth outcomes in neonates: a systematic review and meta-analysis.Frontiers in pediatrics · 2024Pooled it
- Association between vitamin D level and respiratory distress syndrome: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Effect of maternal vitamin D status on risk of adverse birth outcomes: a systematic review and dose-response meta-analysis of observational studies.European journal of nutrition · 2022Pooled it
- Effects of pre-pregnancy body mass index and gestational weight gain on maternal and infant complications.BMC pregnancy and childbirth · 2020Trial
- Pre-pregnancy underweight and obesity are positively associated with small-for-gestational-age infants in a Chinese population.Scientific reports · 2019Trial
- The association between maternal multivitamin intake and premature birth.Scientific reports · 2026Article
- Impact of Maternal Vitamin D Levels on Offspring Bone Development: Systematic Review.Journal of bone metabolism · 2026Article
- Maternal serum concentrations of vitamin D in pregnancy and preterm birth: a case-control study in Southern Sweden.European journal of nutrition · 2025Article
- Saturation effects of pre-pregnancy BMI on infant birth weight in Jiangxi Province, China: a retrospective study.Scientific reports · 2025Article
- Determining the Relationship Between Maternal and Neonatal Vitamin D Serum Levels in Term Infants With and Without Sepsis.Journal of family & reproductive health · 2025Article
- Associations of Vitamin D With GPX4 and Iron Parameters in Chronic Obstructive Pulmonary Disease Patients: A Case-Control Study.Canadian respiratory journal · 2024Article
- Association of 25-Hydroxyvitamin D with Preterm Birth and Premature Rupture of Membranes: A Mendelian Randomization Study.Nutrients · 2023Article
- Vitamin D deficiency in pregnancy and the risk of preterm birth: a nested case-control study.BMC pregnancy and childbirth · 2023Article
- Effects of Nutritional and Social Factors on Favorable Fetal Growth Conditions Using Structural Equation Modeling.Nutrients · 2022Article
- Review
- Article
- Relationship between maternal vitamin D status in the first trimester of pregnancy and maternal and neonatal outcomes: a retrospective single center study.BMC pediatrics · 2021Article
- Low Vitamin D Status Is Associated with Inflammation in Patients with Chronic Obstructive Pulmonary Disease.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Observational
- Associations of Vitamin D Deficiency, Parathyroid hormone, Calcium, and Phosphorus with Perinatal Adverse Outcomes. A Prospective Cohort Study.Nutrients · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gestational vitamin D deficiency (VDD) has been linked with adverse pregnant outcomes. To investigate influent factors of gestational VDD and its relation to the incidence of preterm delivery, total 3598 eligible mother-and-singleton-offspring pairs were recruited. For serum 25(OH)D concentration, 941 pregnant women were sufficient, 1260 insufficient, and 1397 deficient. Further analysis showed that VDD was more prevalent in winter than in other seasons. Underweight but not overweight was a risk factor for gestational VDD. Multivitamin use reduced risk of gestational VDD. Interestingly, 8.23% delivered preterm infants among subjects with VDD (adjusted RR: 4.02; 95% CI: 2.33, 6.92) and 3.81% among subjects with gestational vitamin D insufficiency (VDI) (adjusted RR: 2.07; 95% CI: 1.16, 3.71). Moreover, 2.59% delivered early preterm infants among subjects with VDD (adjusted RR: 2.97; 95% CI: 1.41, 6.24) and 0.49% among subjects with VDI (adjusted RR: 0.54; 95% CI: 0.19, 1.51). The incidence of late preterm delivery was 5.64% among subjects with VDD (adjusted RR: 3.90; 95% CI: 2.26, 6.72) and 3.32% among subjects with VDI (adjusted RR: 2.09; 95% CI: 1.17, 3.74). In conclusion, pre-pregnancy BMI, seasonality and multivitamin use are influent factors of gestational vitamin D status. Gestational VDD is associated with an increased risk of preterm delivery in Chinese population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.