ArticleNature communications2018
An olfactory virtual reality system for mice.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The study of social animal migrations: a synthesis of the past and guidelines for future research.Proceedings. Biological sciences · 2025Pooled it
- A deep reinforcement learning account of competition and integration of visual and goal vector signals for spatial navigation.Scientific reports · 2026Article
- Skin-Integrated Soft Wearable XR Interfaces for Seamless and Realistic User Experience.Chemical reviews · 2025Review
- The Primate Hippocampus Constructs a Temporal Scaffold Anchored to Behavioral Events.bioRxiv : the preprint server for biology · 2025Article
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- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
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- AneLife · 2025Article
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- Integrating Vision and Olfaction via Multi-Modal LLM for Robotic Odor Source Localization.Sensors (Basel, Switzerland) · 2024Article
- How can ethology inform the neuroscience of fear, aggression and dominance?Nature reviews. Neuroscience · 2024Review
- behaviorMate: AnbioRxiv : the preprint server for biology · 2024Article
- Multiphoton imaging of hippocampal neural circuits: techniques and biological insights into region-, cell-type-, and pathway-specific functions.Neurophotonics · 2024Review
- Robotic Odor Source Localization via Vision and Olfaction Fusion Navigation Algorithm.Sensors (Basel, Switzerland) · 2024Article
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- Sequential activity of CA1 hippocampal cells constitutes a temporal memory map for associative learning in mice.Current biology : CB · 2024Article
- Hippocampal sequences span experience relative to rewards.bioRxiv : the preprint server for biology · 2024Article
- The behavioral sensitivity of mice to acyclic, monocyclic, and bicyclic monoterpenes.PloS one · 2024Article
- Odors in space.Frontiers in neural circuits · 2024Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
All motile organisms use spatially distributed chemical features of their surroundings to guide their behaviors, but the neural mechanisms underlying such behaviors in mammals have been difficult to study, largely due to the technical challenges of controlling chemical concentrations in space and time during behavioral experiments. To overcome these challenges, we introduce a system to control and maintain an olfactory virtual landscape. This system uses rapid flow controllers and an online predictive algorithm to deliver precise odorant distributions to head-fixed mice as they explore a virtual environment. We establish an odor-guided virtual navigation behavior that engages hippocampal CA1 "place cells" that exhibit similar properties to those previously reported for real and visual virtual environments, demonstrating that navigation based on different sensory modalities recruits a similar cognitive map. This method opens new possibilities for studying the neural mechanisms of olfactory-driven behaviors, multisensory integration, innate valence, and low-dimensional sensory-spatial processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.