Evidence map›Paper›PMID 29483508›Full record

ArticleBlood cancer journal2018

Protease nexin-1 prevents growth of human B cell lymphoma via inhibition of sonic hedgehog signaling.

Xiangke Xin, Yunchuan Ding, Ying Yang, Xing Fu, Jianfeng Zhou, Chad M McKee, Ruth J Muschel, Robert P Gale, Jane F Apperley, Danmei Xu

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiangke XinDepartment of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China.
Yunchuan DingDepartment of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China.
Ying YangDepartment of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China.ORCID http://orcid.org/0000-0003-4443-4452
Xing FuDepartment of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China.
Jianfeng ZhouDepartment of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China.
Chad M McKeeGray Institute of Radiation Oncology and Biology, Medical Science Division, University of Oxford, Oxford, UK.
Ruth J MuschelGray Institute of Radiation Oncology and Biology, Medical Science Division, University of Oxford, Oxford, UK.
Robert P GaleDepartment of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, Imperial College London, Du Cane road, London, W12 0HS, UK.
Jane F ApperleyDepartment of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, Imperial College London, Du Cane road, London, W12 0HS, UK.
Danmei XuDepartment of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China. danmei.xu@nhs.net.

Funding

Cancer Research UK 20407
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionHedgehog ProteinsHumansLymphoma, Large B-Cell, DiffuseNeoplasm ProteinsSerpin E2Hedgehog ProteinsNeoplasm ProteinsSerpin E2SHH protein, human

Identifiers

PMID29483508
PMCPMC5827524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.