ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2018
Traits of empathy and anger: implications for psychopathy and other disorders associated with aggression.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03863288 (Dose-Response Relationship and Pharmacokinetics of Intranasal Oxytocin on Neural Impact in Youth With High Levels of Irritability), which is not on this map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dose-Response Relationship and Pharmacokinetics of Intranasal Oxytocin on Neural Impact in Youth With High Levels of Irritability
Who cites it
43 citing papers in PubMed, 126 citations in OpenAlex.
- Targeting aggression with prefrontal high-definition transcranial direct current stimulation.Scientific reports · 2026Trial
- Tryptophan-enriched diet or 5-hydroxytryptophan supplementation given in a randomized controlled trial impacts social cognition on a neural and behavioral level.Scientific reports · 2021Trial
- Disruptive behavior in preschoolers: associations with attention deficit hyperactivity disorder and parental psychopathology.BMC psychiatry · 2026Article
- Measuring proactive-instrumental aggression in adolescents and young adults-development and preliminary validity evidence for the Degree-of-Quiz-Difficulty Paradigm.Frontiers in psychology · 2026Article
- Understanding the Etiology of Externalizing Problems in Young Children: The Roles of Callous-Unemotional Traits and Irritability.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Article
- Adults with more severe psychopathy in the community show increased social discounting.Communications psychology · 2025Article
- Article
- Aggression, Suicidality, and Emotion Profiles in Youth: Links to Early Life Adversity.Aggressive behavior · 2025Article
- Role of Resilience in Predicting and Empathy Dimensions in Dental Students: A Cross-Sectional Design.Behavioral sciences (Basel, Switzerland) · 2025Article
- Exploring the Role of Empathy in the Association Between Early Life Adversity and Antisocial Behavior.Affective science · 2025Article
- Why Do They Do It? The Psychology Behind Antisocial Behavior in Children and Adolescents.Pediatric reports · 2025Review
- Implicit intervention approach for empathy: exploring the combined effects of empathic concern and visual perspective-taking.Frontiers in psychiatry · 2025Article
- Psychophysiology of facial emotion recognition in psychopathy dimensions and oxytocin's role: A scoping review.PloS one · 2025Article
- Study Preregistration: Understanding the Etiology of Externalizing Problems in Young Children: The Roles of Callous-Unemotional Traits and Irritability.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Article
- Neuroanatomical correlates of aggressiveness: a case-control voxel- and surface-based morphometric study.Brain structure & function · 2024Article
- Investigating proactive aggression in patients with borderline personality disorder and major depressive disorder using a modified version of the Taylor aggression paradigm.Frontiers in psychology · 2024Article
- A quasi-experimental study in sibling dyads: differential provocation-aggression patterns in the interactive taylor aggression paradigm.Frontiers in psychology · 2024Article
- Dyadic Interactions of Treatment-Resistant Schizophrenia Patients Having Followed Virtual Reality Therapy: A Content Analysis.Journal of clinical medicine · 2023Article
- The positive and negative emotion functions related to loneliness: a systematic review of behavioural and neuroimaging studies.Psychoradiology · 2023Review
- The validation of a Mandarin version of the Empathy Components Questionnaire (ECQ-Chinese) in Chinese samples.PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Empathy and anger are two social emotions that modulate an individual's risk for aggression. Empathy is an emotional reaction to another individual's emotional state. Anger is an emotional reaction to threat, frustration or social provocation. Reduced empathy, seen in psychopathy, increases the risk for goal-directed aggression. Atypically increased anger (i.e. irritability), seen in conditions like disruptive mood dysregulation disorder and borderline personality disorder, increases the risk for reactive aggression. In this paper, I will outline core neurocognitive functions that correspond to empathy and which are compromised in individuals with psychopathic traits. In addition, I will outline neurocognitive functions involved in either the generation or regulation of anger and which are compromised in psychiatric conditions at increased risk for irritability/reactive aggression. It can be hoped that improved understanding of empathy and anger will lead to better assessment tools and improved interventions to reduce aggression risk.This article is part of the theme issue 'Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences'.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.