Evidence map›Paper›PMID 29483292›Full record

ArticleInfection and immunity2018

Coxiella burnetii Subverts p62/Sequestosome 1 and Activates Nrf2 Signaling in Human Macrophages.

Caylin G Winchell, Amanda L Dragan, Katelynn R Brann, Frances I Onyilagha, Richard C Kurten, Daniel E Voth

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Article
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  7. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Review
  10. The intricate dance: host autophagy andFrontiers in microbiology · 2023
    Review
  11. Establishing the intracellular niche of obligate intracellular vacuolar pathogens.Frontiers in cellular and infection microbiology · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Autophagy · 2021
    Article
  18. Review
  19. Biogenesis of the SpaciousInfection and immunity · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Caylin G Winchell *Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Amanda L Dragan *Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Katelynn R BrannDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Frances I OnyilaghaDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Richard C KurtenDepartment of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Daniel E VothDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA dvoth@uams.edu.
University of Arkansas for Medical Sciences · USArkansas Children's Hospital · US

Funding

Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BENOVIC, JEFFREY L · 2013 to 2023
$23.9M
Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
Pilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Jason S Stumhofer · 2022 to 2026
$7.6M
Role of the Coxiella burnetii Cryptic Plasmid in Host Cell ParasitismR01AI087669 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI VOTH, DANIEL E · 2010 to 2014
$1.9M
Characterization of the Human Lung Response to Coxiella burnetii R21AI127931 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI VOTH, DANIEL E · 2017 to 2018
$403k
NHLBI NIH HHS P01 HL114471NIAID NIH HHS R01 AI087669NIAID NIH HHS R21 AI127931NIGMS NIH HHS P20 GM103625NIGMS NIH HHS P30 GM145393
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coxiella burnetiiHost-Pathogen InteractionsHumansMacrophagesNF-E2-Related Factor 2Sequestosome-1 ProteinSignal TransductionNFE2L2 protein, humanNF-E2-Related Factor 2Sequestosome-1 ProteinSQSTM1 protein, humanautophagyCoxiella burnetiiintracellular pathogenNrf2p62

Identifiers

PMID29483292
PMCPMC5913852
OpenAlexW2788694166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.