Evidence map›Paper›PMID 29483280›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Swedish Nerve Growth Factor Mutation (NGF

Kijung Sung, Luiz F Ferrari, Wanlin Yang, ChiHye Chung, Xiaobei Zhao, Yingli Gu, Suzhen Lin, Kai Zhang, Bianxiao Cui, Matthew L Pearn and 4 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Nerve growth factor receptors in equine synovial membranes vary with osteoarthritic disease severity.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  9. Article
  10. Article
  11. The development of somatosensory neurons: Insights into pain and itch.Current topics in developmental biology · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. The NGFThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  19. NT3Stem cell research & therapy · 2019
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

Kijung SungDepartment of Neurosciences.ORCID 0000-0002-9631-8616
Luiz F FerrariDepartment of Oral Surgery, University of California San Francisco, San Francisco, California 94143.ORCID 0000-0002-3831-6428
Wanlin YangDepartment of Neurosciences.
ChiHye ChungDepartment of Biological Sciences, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 143-701, South Korea.ORCID 0000-0002-3104-2399
Xiaobei ZhaoDepartment of Neurosciences.
Yingli GuDepartment of Neurosciences.
Suzhen LinDepartment of Neurosciences.
Kai ZhangDepartment of Chemistry.ORCID 0000-0002-6687-4558
Bianxiao CuiDepartment of Chemistry.ORCID 0000-0002-8044-5629
Matthew L PearnDepartment of Anesthesiology, University of California San Diego, School of Medicine, La Jolla, California 92093.
Michael T MaloneyDepartment of Neurosciences, Stanford University, Stanford, California 94305.
William C MobleyDepartment of Neurosciences.ORCID 0000-0002-6408-9548
Jon D LevineDepartment of Oral Surgery, University of California San Francisco, San Francisco, California 94143.ORCID 0000-0003-0681-5545
Chengbiao WuDepartment of Neurosciences, chw049@ucsd.edu.ORCID 0000-0002-3660-088X
Ruijin Hospital · CNUniversity of California, San Francisco · USHarbin Medical University · CNKonkuk University · KRNeurosciences Institute · USUniversity of California San Diego · USUniversity of Illinois Urbana-Champaign · USVA San Diego Healthcare System · US

Funding

Center for Protein Folding Machinery (RMI)PN2EY016525 · NEI · BAYLOR COLLEGE OF MEDICINE · PI CHIU, WAH · 2005 to 2015
$33.6M
Nociceptor mechanisms in the transition from acute to chronic painR01NS084545 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEVINE, JON DAVID · 2014 to 2018
$3.1M
The role of caveolin-1 on anesthetic-mediated neurotoxicityK08GM124500 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PEARN, MATTHEW L · 2018 to 2022
$1.0M
Center for Protein Folding Machinery (RMI)PN1EY016525 · NEI · BAYLOR COLLEGE OF MEDICINE · PI CHIU, WAH · 2004 to 2004
$67k
NEI NIH HHS PN1 EY016525NEI NIH HHS PN2 EY016525NIGMS NIH HHS K08 GM124500NIGMS NIH HHS L40 GM125142NINDS NIH HHS R01 NS084545
6 · The paper itself

Abstract

Nerve growth factor (NGF) exerts multiple functions on target neurons throughout development. The recent discovery of a point mutation leading to a change from arginine to tryptophan at residue 100 in the mature NGFβ sequence (NGF

Indexed as

Mutation, MissenseNociception3T3 CellsAnimalsCells, CulturedHEK293 CellsHereditary Sensory and Autonomic NeuropathiesHumansMaleMiceNerve Growth FactorNerve Tissue ProteinsPC12 CellsProtein BindingRatsRats, Sprague-DawleyNerve Growth FactorNerve Tissue ProteinsNgfr protein, ratReceptors, Growth FactorReceptors, Nerve Growth FactorReceptor, trkANGFnociceptionp75sensory neuronTrkAtrophic

Identifiers

PMID29483280
PMCPMC5895035
OpenAlexW2789091867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.