Evidence map›Paper›PMID 29483256›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Forecasting the spatial transmission of influenza in the United States.

Sen Pei, Sasikiran Kandula, Wan Yang, Jeffrey Shaman

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Reconstructing the early spatial spread of pandemic respiratory viruses in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Data assimilation for estimating time-varying reproduction numbers.Journal of the Royal Society, Interface · 2025
    Article
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  13. Inferring pathogen superspreading potential using early spatial spread patterns.medRxiv : the preprint server for health sciences · 2025
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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sen PeiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032 sp3449@cumc.columbia.edu jls106@cumc.columbia.edu.ORCID 0000-0002-7072-2995
Sasikiran KandulaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032.
Wan YangDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032.
Jeffrey ShamanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032 sp3449@cumc.columbia.edu jls106@cumc.columbia.edu.

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Ami R Zota · 1998 to 2026
$44.7M
Development and Dissemination of Operational Real-Time Respiratory Virus ForecastU01GM110748 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2014 to 2018
$2.6M
Influenza Outbreak Prediction: Applying Data Assimilation Methodology to Make...R01GM100467 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2011 to 2015
$1.4M
NIEHS NIH HHS P30 ES009089NIGMS NIH HHS R01 GM100467NIGMS NIH HHS U01 GM110748
6 · The paper itself

Abstract

Recurrent outbreaks of seasonal and pandemic influenza create a need for forecasts of the geographic spread of this pathogen. Although it is well established that the spatial progression of infection is largely attributable to human mobility, difficulty obtaining real-time information on human movement has limited its incorporation into existing infectious disease forecasting techniques. In this study, we develop and validate an ensemble forecast system for predicting the spatiotemporal spread of influenza that uses readily accessible human mobility data and a metapopulation model. In retrospective state-level forecasts for 35 US states, the system accurately predicts local influenza outbreak onset,-i.e., spatial spread, defined as the week that local incidence increases above a baseline threshold-up to 6 wk in advance of this event. In addition, the metapopulation prediction system forecasts influenza outbreak onset, peak timing, and peak intensity more accurately than isolated location-specific forecasts. The proposed framework could be applied to emergent respiratory viruses and, with appropriate modifications, other infectious diseases.

Indexed as

ForecastingHumansInfluenza, HumanModels, StatisticalRetrospective StudiesSeasonsUnited Statesdata assimilationhuman mobilityinfluenza forecastmetapopulation modelspatial transmission

Identifiers

PMID29483256
PMCPMC5856508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.