ArticleJournal of the American Society of Nephrology : JASN2018
Mechanism of Hyperkalemia-Induced Metabolic Acidosis.
Open access · greenAbstract read
In one paragraph
Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Efficacy and safety of oral sodium bicarbonate in kidney-transplant recipients and non-transplant patients with chronic kidney disease: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- The kidney distal tubule potassium switch, modern diet and hypertension.Nature reviews. Nephrology · 2026Review
- Nanomachines Based on Inner Ultrasonic Multiple Scattering for Ameliorating Renal Function.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Effects of proximal tubule NBCe1-A deletion on collecting duct intercalated cell responses to hypokalemia.American journal of physiology. Renal physiology · 2026Article
- Renal NHE3 is required to limit hypokalemia and metabolic acidosis during dietary potassium deficiency.Pflugers Archiv : European journal of physiology · 2026Article
- Dietary potassium restriction causes hypercalciuria, hypocalcemia, and bone loss in male mice.JCI insight · 2026Article
- [Consensus recommendations on the diagnosis and treatment of hyperkalemia of the Austrian Society of Nephrology 2026].Wiener klinische Wochenschrift · 2026Review
- Diabetic Ketoacidosis: Considerations and Residual Controversies in Management After the 2024 ADA, EASD, JBDS, AACE, and DST Joint ConsensusEndocrine, metabolic & immune disorders drug targets · 2026Review
- Machine Learning Techniques for the Analysis of the Influence of Blood Gasometry Parameters on Acid-Base Homeostasis in Pediatric Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Calcineurin Inhibitors: Current Role, Toxicity Management, and Future Frontiers in Immunosuppression.Molecular neurobiology · 2025Review
- Sex differences in renal acid-base regulation.American journal of physiology. Renal physiology · 2025Article
- The association between potassium level during the anhepatic stage of orthotopic liver transplantation and postoperative acute kidney injury: an exploratory study.BMC nephrology · 2025Observational
- Hyperkalemia and maintenance of renin-angiotensin system inhibitor therapy after initiating SGLT-2 or DPP-4 inhibitors.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Biology of the proximal tubule in body homeostasis and kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Nutrition support for patients with renal dysfunction in the intensive care unit: A narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Review
- Role of KThe American journal of pathology · 2025Article
- Familial Hyperkalemic Hypertension.Comprehensive Physiology · 2024Review
- Revisiting voltage-coupled HAmerican journal of physiology. Renal physiology · 2024Review
- Distal convoluted tubule-specific disruption of the COP9 signalosome but not its regulatory target cullin 3 causes tubular injury.American journal of physiology. Renal physiology · 2024Article
- Hyperglycaemic crises in adults with diabetes: a consensus report.Diabetologia · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Autumn N HarrisDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.ORCID 0000-0002-2329-3905
P Richard GrimmDepartment of Physiology and Maryland Center for Kidney Discovery, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0002-9368-0601
Hyun-Wook LeeDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.
Eric DelpireDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee; and.ORCID 0000-0002-3702-1599
Lijuan FangDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.
Jill W VerlanderDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida.ORCID 0000-0002-4096-4897
Paul A WellingDepartment of Physiology and Maryland Center for Kidney Discovery, University of Maryland School of Medicine, Baltimore, Maryland.
I David WeinerDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida; david.weiner@medicine.ufl.edu.ORCID 0000-0002-0046-0600
University of Florida · USUniversity of Maryland, Baltimore · USUnited States Department of Veterans Affairs · USVanderbilt University Medical Center · US
Funding
WNK-SPAK signaling in the Distal NephronR01DK093501 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, Paul A Welling · 2012 to 2026
$12.1MMolecular of ROMK Channel FunctionR01DK054231 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI Paul A Welling · 1998 to 2026
$7.7MOXGR1 in Renal Intercalated Cells, Salt Transport and Diuretic EfficacyR01DK110375 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, SUSAN MARIE WALL · 2017 to 2026
$6.7MH/HCO3 transport in the collecting ductR01DK045788 · NIDDK · UNIVERSITY OF FLORIDA · PI WEINER, I. DAVID · 2000 to 2017
$4.4MMolecular Mechanisms Regulating Ammonia MetabolismR01DK107798 · NIDDK · UNIVERSITY OF FLORIDA · PI WEINER, I. DAVID · 2016 to 2025
$3.2MREnal TrAIning & reteNtion (RETAIN) ProgramT32DK104721 · NIDDK · UNIVERSITY OF FLORIDA · PI SEGAL, MARK S., WOOD, CHARLES E · 2015 to 2019
$1.6MNIDDK NIH HHS R01 DK045788NIDDK NIH HHS R01 DK054231NIDDK NIH HHS R01 DK093501NIDDK NIH HHS R01 DK107798NIDDK NIH HHS R01 DK110375NIDDK NIH HHS T32 DK104721
Abstract
PubMed holds no abstract for this paper.
Indexed as
AcidosisAldosteroneAmilorideAmmoniaAnimalsCation Transport ProteinsDiureticsGlutaminaseHydrochlorothiazideHydrogen-Ion ConcentrationHyperkalemiaKidney Tubules, DistalKidney Tubules, ProximalMembrane GlycoproteinsMiceMice, KnockoutAldosteroneAmilorideAmmoniabenzamilCation Transport ProteinsDiureticsGlutaminaseHydrochlorothiazideMembrane GlycoproteinsProtein Serine-Threonine KinasesProton-Translocating ATPasesRhcg protein, mouseStk39 protein, mousechronic metabolic acidosiscollecting ductsproximal tubulerenal tubular acidosis
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.