Evidence map›Paper›PMID 29483152›Full record

ArticleGenes & development2018

Daniel P Reich, Katarzyna M Tyc, Brenda L Bass

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
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  6. ADARs mediate distinct RNA editing activity and gene regulation in thebioRxiv : the preprint server for biology · 2025
    Article
  7. Article
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  12. The importance of IP6 for ADAR RNA-editing enzymes and antiviral defense.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. ADR-2 regulates fertility and oocyte fate inbioRxiv : the preprint server for biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel P ReichDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.
Katarzyna M TycDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.
Brenda L BassDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.
University of Utah · US

Funding

DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007491 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI James Alan Gagnon, Kristen M Kwan · 1995 to 2026
$8.0M
The Biology and Biochemistry of ADAR RNA Editing EnzymesR01GM044073 · NIGMS · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 1990 to 2020
$3.6M
Cellular double-stranded RNA as a signal of stress, immunity, and aging.DP1AG044162 · NIA · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 2012 to 2015
$3.0M
NIA NIH HHS DP1 AG044162NICHD NIH HHS T32 HD007491NIGMS NIH HHS R01 GM044073
6 · The paper itself

Abstract

Cellular dsRNAs are edited by adenosine deaminases that act on RNA (ADARs). While editing can alter mRNA-coding potential, most editing occurs in noncoding sequences, the function of which is poorly understood. Using dsRNA immunoprecipitation (dsRIP) and RNA sequencing (RNA-seq), we identified 1523 regions of clustered A-to-I editing, termed editing-enriched regions (EERs), in four stages of

Indexed as

RNA EditingRNA InterferenceAdenosineAdenosine DeaminaseAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsInosineMutationRibonuclease IIIRNA-Dependent RNA PolymeraseRNA, Double-StrandedRNA, Small InterferingAdenosineAdenosine DeaminaseAdr-1 protein, C elegansAdr-2 protein, C elegansCaenorhabditis elegans Proteinsdcr-1 protein, C elegansInosineRibonuclease IIIRNA-Dependent RNA PolymeraseRNA-directed RNA polymerase RRF-3, C elegansRNA, Double-StrandedRNA, Small InterferingdeaminaseDicerRNA editingself–nonselfsiRNA

Identifiers

PMID29483152
PMCPMC5859968
OpenAlexW2788540939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.