ArticleBMJ open diabetes research & care2018
Serum creatinine levels and risk of incident type 2 diabetes mellitus or dysglycemia in middle-aged Japanese men: a retrospective cohort study.
Article in BMJ open diabetes research & care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- Comprehensive machine learning models for predicting therapeutic targets in type 2 diabetes utilizing molecular and biochemical features in rats.Frontiers in endocrinology · 2024Article
- Constipation anti-aging effects by dairy-based lactic acid bacteria.Journal of animal science and technology · 2024Article
- Integrated biomarker profiling of the metabolome associated with type 2 diabetes mellitus among Tibetan in China.Diabetology & metabolic syndrome · 2023Article
- Association between serum creatinine and type 2 diabetes in the Chinese population: a retrospective cohort study.Scientific reports · 2023Article
- Arsenic Secondary Methylation Capacity Is Inversely Associated with Arsenic Exposure-Related Muscle Mass Reduction.International journal of environmental research and public health · 2021Article
- Fermented pork fat (Sa-um) and lifestyle risk factors as potential indicators for type 2 diabetes among the Mizo population, Northeast India.Journal of health, population, and nutrition · 2021Article
- A Preliminary Study Showing the Impact of Genetic and Dietary Factors on GC-MS-Based Plasma Metabolome of Patients with and withoutCurrent issues in molecular biology · 2021Article
- Creatinine to Body Weight Ratio Is Associated with Incident Diabetes: Population-Based Cohort Study.Journal of clinical medicine · 2020Article
- Low serum creatinine and risk of diabetes: The Japan Epidemiology Collaboration on Occupational Health Study.Journal of diabetes investigation · 2019Article
- Insulin Sensitivity Is Associated with Lipoprotein Lipase (International journal of molecular sciences · 2019Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the association between low serum creatinine levels and an increased risk of type 2 diabetes mellitus and dysglycemia. RESEARCH DESIGN AND
methodsWe conducted a retrospective cohort study of 3313 Japanese male workers aged 30-55 years, who underwent annual health check-ups during 2001-2008 and showed no type 2 diabetes mellitus, and underwent follow-up examinations until March 2013. Dysglycemia was defined as a fasting plasma glucose concentration of
resultsDuring the median 6.7-year follow-up, there were 207 cases of incident type 2 diabetes mellitus and 596 cases of incident dysglycemia, including 115 cases of type 2 diabetes mellitus among the subjects with normal glucose concentrations at baseline. After adjustment for age, body mass index and known diabetes risk factors, the multivariable HR of type 2 diabetes mellitus for the lowest category of serum creatinine (<0.7 mg/dL) vs the highest category (0.9-1.1 mg/dL) was 1.9 (95% CI 1.2 to 2.9; P for trend 0.03). The multivariable HRs of dysglycemia for the lowest category of serum creatinine versus the highest category was 1.5 (95% CI 1.1 to 1.9; P for trend 0.01).
conclusionsLow serum creatinine levels were associated with an increased risk of type 2 diabetes mellitus and dysglycemia.
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