Evidence map›Paper›PMID 29483125›Full record

ArticleAntimicrobial agents and chemotherapy2018

Treatment of Clostridium difficile Infection with a Small-Molecule Inhibitor of Toxin UDP-Glucose Hydrolysis Activity.

Ilana L Stroke, Jeffrey J Letourneau, Teresa E Miller, Yan Xu, Igor Pechik, Diana R Savoly, Linh Ma, Laurie J Sturzenbecker, Joan Sabalski, Philip D Stein and 2 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ilana L Stroke *Venenum Biodesign, Hamilton, New Jersey, USA.
Jeffrey J Letourneau *Venenum Biodesign, Hamilton, New Jersey, USA.
Teresa E MillerFemeris Women's Health Research Center, Hamilton, New Jersey, USA.
Yan XuInvivotek, Hamilton, New Jersey, USA.
Igor PechikVenenum Biodesign, Hamilton, New Jersey, USA.
Diana R SavolyVenenum Biodesign, Hamilton, New Jersey, USA.
Linh MaVenenum Biodesign, Hamilton, New Jersey, USA.
Laurie J SturzenbeckerVenenum Biodesign, Hamilton, New Jersey, USA.
Joan SabalskiVenenum Biodesign, Hamilton, New Jersey, USA.
Philip D SteinVenenum Biodesign, Hamilton, New Jersey, USA.
Maria L WebbVenenum Biodesign, Hamilton, New Jersey, USA.
David W HilbertFemeris Women's Health Research Center, Hamilton, New Jersey, USA dhilbert@mdlab.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsCell LineCell SurvivalClostridioides difficileClostridium InfectionsColonCricetinaeHumansHydrolysisMiceUridine Diphosphate GlucoseAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsUridine Diphosphate GlucoseClostridium difficiletoxin-mediated diseases

Identifiers

PMID29483125
PMCPMC5923158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.