Evidence map›Paper›PMID 29483123›Full record

ArticleAntimicrobial agents and chemotherapy2018

Micafungin Enhances the Human Macrophage Response to Candida albicans through β-Glucan Exposure.

José Pedro Guirao-Abad, Ruth Sánchez-Fresneda, Francisco Machado, Juan Carlos Argüelles, María Martínez-Esparza

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Loss of Fgr41 inInfection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Baicalin promotes β-1,3-glucan exposure inFrontiers in cellular and infection microbiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Echinocandins - structure, mechanism of action and use in antifungal therapy.Journal of enzyme inhibition and medicinal chemistry · 2022
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

José Pedro Guirao-AbadDepartamento de Microbiología, Facultad de Biología, Universidad de Murcia, Murcia, Spain jpguirao@hotmail.com maria@um.es.
Ruth Sánchez-FresnedaDepartamento de Microbiología, Facultad de Biología, Universidad de Murcia, Murcia, Spain.
Francisco MachadoServicio de Ginecología y Obstetricia, Hospital Universitario Virgen de la Arrixaca, IMIB, Murcia, Spain.
Juan Carlos ArgüellesDepartamento de Microbiología, Facultad de Biología, Universidad de Murcia, Murcia, Spain.
María Martínez-EsparzaDepartamento de Bioquímica, Biología Molecular (B) e Inmunología, Facultad de Medicina, IMIB and Regional Campus of International Excellence Campus Mare Nostrum, Universidad de Murcia, Murcia, Spain jpguirao@hotmail.com maria@um.es.
Universidad de Murcia · ESHospital Universitario Virgen de la Arrixaca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micafungin belongs to the antifungal family of echinocandins, which act as noncompetitive inhibitors of the fungal cell wall β-1,3-d-glucan synthase. Since

Indexed as

Antifungal AgentsCandida albicansCandidiasisCell WallGlucosyltransferasesHumansInflammationInterleukin-10Interleukin-17MacrophagesMicafunginMicrobial Sensitivity TestsTumor Necrosis Factor-alphaAntifungal Agentsbeta-1,3-D-glucan synthetase, Candida albicansGlucosyltransferasesIL10 protein, humanIL17A protein, humanInterleukin-10Interleukin-17MicafunginTumor Necrosis Factor-alphaantifungalCandida albicanschitincytokinemacrophagemicafunginβ-glucans

Identifiers

PMID29483123
PMCPMC5923102
OpenAlexW2793739354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.