Evidence map›Paper›PMID 29483117›Full record

ArticleAntimicrobial agents and chemotherapy2018

Identification and Characterization of Key Charged Residues in the Cofilin Protein Involved in Azole Susceptibility, Apoptosis, and Virulence of Aspergillus fumigatus.

Zhongyi Lu, Xiaodong Jia, Yong Chen, Xuelin Han, Fangyan Chen, Shuguang Tian, Xueting Su, Zongwei Li, Jingya Zhao, Xi Zhang and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. A Cecropin-4 Derived Peptide C18 InhibitsFrontiers in microbiology · 2022
    Article
  4. Article
  5. Virulence · 2021
    Review
  6. Low Glucose Mediated Fluconazole Tolerance inJournal of fungi (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zhongyi LuAcademy of Military Medical Sciences, Academy of Military Sciences, PLA, Beijing, China.
Xiaodong JiaInstitute for Disease Control and Prevention of PLA, Beijing, China.
Yong ChenInstitute for Disease Control and Prevention of PLA, Beijing, China.
Xuelin HanInstitute for Disease Control and Prevention of PLA, Beijing, China.
Fangyan ChenInstitute for Disease Control and Prevention of PLA, Beijing, China.
Shuguang TianInstitute for Disease Control and Prevention of PLA, Beijing, China.
Xueting SuInstitute for Disease Control and Prevention of PLA, Beijing, China.
Zongwei LiInstitute for Disease Control and Prevention of PLA, Beijing, China.
Jingya ZhaoInstitute for Disease Control and Prevention of PLA, Beijing, China.
Xi ZhangAcademy of Military Medical Sciences, Academy of Military Sciences, PLA, Beijing, China.
Mandong HuAcademy of Military Medical Sciences, Academy of Military Sciences, PLA, Beijing, China.
Liuyu HuangAcademy of Military Medical Sciences, Academy of Military Sciences, PLA, Beijing, China huangliuyuly@163.com hanlicdc@163.com.
Li HanAcademy of Military Medical Sciences, Academy of Military Sciences, PLA, Beijing, China huangliuyuly@163.com hanlicdc@163.com.
Beijing Center for Disease Prevention and Control · CNAcademy of Military Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through some specific amino acid residues, cofilin, a ubiquitous actin depolymerization factor, can significantly affect mitochondrial function related to drug resistance and apoptosis in

Indexed as

Acetyl Coenzyme AActin Depolymerizing FactorsAntifungal AgentsApoptosisAspergillus fumigatusATP-Binding Cassette TransportersAzolesCytochrome P-450 Enzyme SystemDrug Resistance, FungalErgosterolFungal ProteinsHumansMitochondriaVirulenceAcetyl Coenzyme AActin Depolymerizing FactorsAntifungal AgentsATP-Binding Cassette TransportersAzolescytochrome P-450 CYP51A, Aspergilluscytochrome P-450 CYP51B, AspergillusCytochrome P-450 Enzyme SystemErgosterolFungal ProteinsapoptosisAspergillus fumigatusazole susceptibilitycofilinmitochondriavirulence

Identifiers

PMID29483117
PMCPMC5923094
OpenAlexW2794600639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.