Evidence map›Paper›PMID 29483113›Full record

ArticleAntimicrobial agents and chemotherapy2018

The Amphibian Antimicrobial Peptide Temporin B Inhibits

M E Marcocci, D Amatore, S Villa, B Casciaro, P Aimola, G Franci, P Grieco, M Galdiero, A T Palamara, M L Mangoni and 1 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Antifungal peptides from living organisms.Frontiers in microbiology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Temporins: Multifunctional Peptides from Frog Skin.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Designed Multifunctional Peptides for Intracellular Targets.Antibiotics (Basel, Switzerland) · 2022
    Review
  18. Review
  19. Article
  20. Antifungal Activity of the Frog Skin Peptide Temporin G and Its Effect onInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M E Marcocci *Department of Public Health and Infectious Diseases, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.ORCID 0000-0003-4751-4263
D Amatore *Department of Public Health and Infectious Diseases, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.ORCID 0000-0001-5701-9683
S VillaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
B CasciaroDepartment of Biochemical Sciences, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
P AimolaDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
G FranciDepartment of Experimental Medicine, University of Study of Campania Luigi Vanvitelli, Naples, Italy.
P GriecoDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
M GaldieroDepartment of Experimental Medicine, University of Study of Campania Luigi Vanvitelli, Naples, Italy.
A T PalamaraDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.ORCID 0000-0001-8330-4381
M L Mangoni *Department of Biochemical Sciences, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.ORCID 0000-0002-5991-5868
L Nencioni *Department of Public Health and Infectious Diseases, Sapienza University of Rome, and Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy lucia.nencioni@uniroma1.it.ORCID 0000-0003-4427-4823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The herpes simplex virus 1 (HSV-1) is widespread in the population, and in most cases its infection is asymptomatic. The currently available anti-HSV-1 drugs are acyclovir and its derivatives, although long-term therapy with these agents can lead to drug resistance. Thus, the discovery of novel antiherpetic compounds deserves additional effort. Naturally occurring antimicrobial peptides (AMPs) represent an interesting class of molecules with potential antiviral properties. To the best of our knowledge, this study is the first demonstration of the

Indexed as

AnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesAntiviral AgentsMicroscopy, Electron, TransmissionProteinsSimplexvirusAnti-Infective AgentsAntimicrobial Cationic PeptidesAntiviral AgentsProteinstemporinantimicrobial peptideantiviral agentsHSV-1temporinvirucidal

Identifiers

PMID29483113
PMCPMC5923125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.