ArticleCirculation2018
Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests.
Article in Circulation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 80 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- an Observational Study
Drone Delivery of Automated External Defibrillators to Lay Users (DAEDALUS): A Proof of Concept Study
Association of Prehospital Endotracheal Intubation With 28-Day Survival and Neurological Outcomes in Out-of-Hospital Cardiac Arrest
Who cites it
80 citing papers in PubMed, 2 syntheses or guidelines pooled it, 195 citations in OpenAlex.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 2. Current status of cardiac arrest and the chain of survival.Clinical and experimental emergency medicine · 2026Guideline
- 2020 Korean Guidelines for Cardiopulmonary Resuscitation. Part 9. Education and system implementation for enhanced chain of survival.Clinical and experimental emergency medicine · 2021Guideline
- Survival to intensive care unit discharge among in-hospital cardiac arrest patients by applying audiovisual feedback device.ESC heart failure · 2021Trial
- Feasibility of multi-domain data acquisition in patients at risk for hypoxic-ischemic brain injury following cardiac arrest: a prospective cohort study.Resuscitation plus · 2026Article
- Psychological barriers to bystander AED use: Associations of empathy with willingness to perform bystander rescue behaviors.Resuscitation plus · 2026Article
- Racial and Geographic Disparities in Automated External Defibrillator Use During EMS Encounters in the United States.Healthcare (Basel, Switzerland) · 2026Article
- Reducing Racial Disparities in Bystander CPR: Psychological and Environmental Determinants of Hands-Only CPR Willingness in African American Communities.Journal of racial and ethnic health disparities · 2026Article
- Bystander placement of automated external defibrillators and out-of-hospital cardiac arrest outcomes: a propensity score-matched cohort study between 2021 and 2022.Internal and emergency medicine · 2026Article
- Epidemiology and outcomes of out-of-hospital cardiac arrests at sport and recreational events in England, 2015-2022.Resuscitation plus · 2026Article
- Public-private partnerships for UAV-assisted emergency medical services in aging communities: an evolutionary game approach.Frontiers in public health · 2026Article
- Clinical and laboratory predictors of 28-day survival and neurologic outcome in out-of-hospital cardiac arrest: A prospective cohort study.Irish journal of medical science · 2025Observational
- Eligibility and hypothetical time windows for eCPR in out-of-hospital cardiac arrest patients managed by a nationwide helicopter-emergency medical service: A multicentric, retrospective cohort study.Resuscitation plus · 2025Article
- Assessing admitted patients' preparedness during mass casualty incidents at the hospital - a prospective study.Israel journal of health policy research · 2025Article
- Epidemiology and outcomes of out-of-hospital cardiac arrests treated by an anaesthetist-staffed emergency medical service: a 3-year registry analysis in The Friuli-Venezia-Giulia region.Resuscitation plus · 2025Article
- Protocol for a parallel-group, superiority randomized controlled trial of the PulsePoint mobile application to increase bystander resuscitation in out-of-hospital cardiac arrest.Resuscitation plus · 2025Article
- Factors influencing willingness to perform cardiopulmonary resuscitation (CPR) and use an automated external defibrillator (AED) among non-healthcare community participants in a CPR fun run.BMC public health · 2025Article
- Out-of-Hospital Cardiac Arrest in US Airports.JAMA network open · 2025Article
- Bystander availability, CPR uptake, and AED use during out-of-hospital cardiac arrest.Resuscitation plus · 2025Article
- Are high school cardiopulmonary resuscitation education mandates working? Insights from a high school survey on CPR knowledge, attitudes, and readiness.Heart rhythm · 2025Observational
- Public awareness of automated external defibrillator (AED)s and their location: Results of a cross-sectional survey in North Carolina.Resuscitation plus · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
20 authors at 13 institutions in 2 countries.
Funding
Abstract
backgroundSurvival following out-of-hospital cardiac arrest (OHCA) with shockable rhythms can be improved with early defibrillation. Although shockable OHCA accounts for only ≈25% of overall arrests, ≈60% of public OHCAs are shockable, offering the possibility of restoring thousands of individuals to full recovery with early defibrillation by bystanders. We sought to determine the association of bystander automated external defibrillator use with survival and functional outcomes in shockable observed public OHCA.
methodsFrom 2011 to 2015, the Resuscitation Outcomes Consortium prospectively collected detailed information on all cardiac arrests at 9 regional centers. The exposures were shock administration by a bystander-applied automated external defibrillator in comparison with initial defibrillation by emergency medical services. The primary outcome measure was discharge with normal or near-normal (favorable) functional status defined as a modified Rankin Score ≤2. Survival to hospital discharge was the secondary outcome measure.
resultsAmong 49 555 OHCAs, 4115 (8.3%) observed public OHCAs were analyzed, of which 2500 (60.8%) were shockable. A bystander shock was applied in 18.8% of the shockable arrests. Patients shocked by a bystander were significantly more likely to survive to discharge (66.5% versus 43.0%) and be discharged with favorable functional outcome (57.1% versus 32.7%) than patients initially shocked by emergency medical services. After adjusting for known predictors of outcome, the odds ratio associated with a bystander shock was 2.62 (95% confidence interval, 2.07-3.31) for survival to hospital discharge and 2.73 (95% confidence interval, 2.17-3.44) for discharge with favorable functional outcome. The benefit of bystander shock increased progressively as emergency medical services response time became longer.
conclusionsBystander automated external defibrillator use before emergency medical services arrival in shockable observed public OHCA was associated with better survival and functional outcomes. Continued emphasis on public automated external defibrillator utilization programs may further improve outcomes of OHCA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.