Evidence map›Paper›PMID 29482721›Full record

ArticleeLife2018

Vibrator and PI4KIIIα govern neuroblast polarity by anchoring non-muscle myosin II.

Chwee Tat Koe, Ye Sing Tan, Max Lönnfors, Seong Kwon Hur, Christine Siok Lan Low, Yingjie Zhang, Pakorn Kanchanawong, Vytas A Bankaitis, Hongyan Wang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Arf1 and ARFGEF2/Sec71 control neuroblast polarity by anchoring nonmuscle myosin II.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Courier service for phosphatidylinositol: PITPs deliver on demand.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2021
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Lipid Mediated Regulation of Adult Stem Cell Behavior.Frontiers in cell and developmental biology · 2020
    Review
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Chwee Tat KoeNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0003-0940-125X
Ye Sing TanNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, Singapore, Singapore.
Max LönnforsDepartment of Molecular and Cellular Medicine, Texas A&M University Health Science Center, College Station, United States.
Seong Kwon HurDepartment of Molecular and Cellular Medicine, Texas A&M University Health Science Center, College Station, United States.
Christine Siok Lan LowMechanobiology Institute, National University of Singapore, Singapore, Singapore.
Yingjie ZhangNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, Singapore, Singapore.
Pakorn KanchanawongMechanobiology Institute, National University of Singapore, Singapore, Singapore.
Vytas A BankaitisDepartment of Molecular and Cellular Medicine, Texas A&M University Health Science Center, College Station, United States.
Hongyan WangNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0003-4623-1878
National University of Singapore · SGTexas A&M Health Science Center · USDuke-NUS Medical School · SG

Funding

Functional Anatomy of Mammalian Phosphatidylinositol Transfer ProteinsR01GM112591 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI BANKAITIS, VYTAS A · 2015 to 2018
$1.7M
NIGMS NIH HHS R01 GM112591NIGMS NIH HHS RO1GM112591
6 · The paper itself

Abstract

A central feature of most stem cells is the ability to self-renew and undergo differentiation via asymmetric division. However, during asymmetric division the role of phosphatidylinositol (PI) lipids and their regulators is not well established. Here, we show that the sole type I PI transfer protein, Vibrator, controls asymmetric division of

Indexed as

Cell PolarityAnimalsBrainDrosophilaDrosophila ProteinsLarvaMinor Histocompatibility AntigensMyosin Type IINeural Stem CellsPhospholipid Transfer ProteinsPhosphotransferases (Alcohol Group Acceptor)Protein BindingDrosophila ProteinsMinor Histocompatibility AntigensMyosin Type IIphosphatidylinositol phosphate 4-kinasePhospholipid Transfer ProteinsPhosphotransferases (Alcohol Group Acceptor)Sqh protein, DrosophilaVib protein, Drosophilaasymmetric divisiondevelopmental biologyD. melanogasterDrosophilaneuroblastneurosciencephosphatidylinositol lipidsstem cells

Identifiers

PMID29482721
PMCPMC5828666
OpenAlexW2788736927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.