ArticleMicrobiome2018
A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses.
Article in Microbiome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 68 citations in OpenAlex.
- Orally administratedFrontiers in immunology · 2023Trial
- Genomic landscape of the human vaginal microbiome is linked to host genetics and population of origin.Nature genetics · 2026Article
- Disentangling host identity and storage time effects on gut microbiota composition in captive migratory birds using absolute and relative quantification.Current zoology · 2026Article
- Comparative study of sample storage conditions on gut dysbiosis in peripheral artery disease.Research square · 2025Article
- Unraveling the impact of host genetics and factors on the urinary microbiome in a young population.mBio · 2024Article
- Integrated large-scale metagenome assembly and multi-kingdom network analyses identify sex differences in the human nasal microbiome.Genome biology · 2024Article
- Insights into the assembly of the neovaginal microbiota in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients.Nature communications · 2024Article
- Consistent signatures in the human gut microbiome of old- and young-onset colorectal cancer.Nature communications · 2024Article
- Quantifying bias introduced by sample collection in relative and absolute microbiome measurements.Nature biotechnology · 2024Article
- A workflow for the detection of antibiotic residues, measurement of water chemistry and preservation of hospital sink drain samples for metagenomic sequencing.The Journal of hospital infection · 2024Article
- The impact of storage buffer and storage conditions on fecal samples for bacteriophage infectivity and metavirome analyses.Microbiome · 2023Article
- Article
- Intermittent fasting modulates the intestinal microbiota and improves obesity and host energy metabolism.NPJ biofilms and microbiomes · 2023Article
- Water Extract ofNutrients · 2023Article
- Life History Recorded in the Vagino-cervical Microbiome Along with Multi-omes.Genomics, proteomics & bioinformatics · 2022Article
- Over 50,000 Metagenomically Assembled Draft Genomes for the Human Oral Microbiome Reveal New Taxa.Genomics, proteomics & bioinformatics · 2022Article
- Effect of Plant-Derived n-3 Polyunsaturated Fatty Acids on Blood Lipids and Gut Microbiota: A Double-Blind Randomized Controlled Trial.Frontiers in nutrition · 2022Article
- Standards for Collection, Preservation, and Transportation of Fecal Samples in TCM Clinical Trials.Frontiers in cellular and infection microbiology · 2022Article
- Article
- Comparison of Fecal Collection Methods on Variation in Gut Metagenomics and Untargeted Metabolomics.mSphere · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 3 countries.
Funding
Abstract
backgroundThe number of large-scale studies on the gut microbiota in human cohorts is rapidly increasing. However, the few and expensive options for storage of fecal samples at room temperature have been an obstacle for large-scale metagenomic studies and the development of clinical/commercial personal metagenomic sequencing.
resultsIn this study, we systematically tested a novel N-octylpyridinium bromide-based fecal sample preservation method and compared it with other currently used storage methods. We found that the N-octylpyridinium bromide-based method enabled preservation of the bacterial composition in fecal samples transported and stored at room temperature for up to at least 14 days.
conclusionsWe describe a novel chemical stabilizer that allows cost-effective transportation and storage at room temperature for several days with preservation of bacterial composition. This method will facilitate sample collection even in remote area and also enable transport via normal commercial transportation routes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.