Evidence map›Paper›PMID 29482645›Full record

ArticleBMC veterinary research2018

Prevalence of hepatitis E virus infection in wild boars from Spain: a possible seasonal pattern?

Antonio Rivero-Juarez, María A Risalde, Mario Frias, Ignacio García-Bocanegra, Pedro Lopez-Lopez, David Cano-Terriza, Angela Camacho, Saul Jimenez-Ruiz, Jose C Gomez-Villamandos, Antonio Rivero

Abstract read
In one paragraph

Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Clinical Burden of Symptomatic HEV-3 Infection in Southern Spain.Alimentary pharmacology & therapeutics · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Prevalence ofOne health (Amsterdam, Netherlands) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Common Mosquito (Frontiers in veterinary science · 2022
    Article
  14. Article
  15. Article
  16. Detection of Hepatitis E Virus inFrontiers in microbiology · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antonio Rivero-JuarezInfectious Diseases Unit. Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía de Córdoba. Universidad de Córdoba, 2° Floor. Box 134.Avenida Menendez Pidal s/n, 14004, Córdoba, Spain. arjvet@gmail.com.ORCID http://orcid.org/0000-0002-5813-6889
María A RisaldeInfectious Diseases Unit. Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía de Córdoba. Universidad de Córdoba, 2° Floor. Box 134.Avenida Menendez Pidal s/n, 14004, Córdoba, Spain.
Mario FriasInfectious Diseases Unit. Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía de Córdoba. Universidad de Córdoba, 2° Floor. Box 134.Avenida Menendez Pidal s/n, 14004, Córdoba, Spain.
Ignacio García-BocanegraAnimal Health Department. Veterinary Science College, Universidad de Córdoba, 14014, Cordoba, Spain.
Pedro Lopez-LopezInfectious Diseases Unit. Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía de Córdoba. Universidad de Córdoba, 2° Floor. Box 134.Avenida Menendez Pidal s/n, 14004, Córdoba, Spain.
David Cano-TerrizaAnimal Health Department. Veterinary Science College, Universidad de Córdoba, 14014, Cordoba, Spain.
Angela CamachoInfectious Diseases Unit. Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía de Córdoba. Universidad de Córdoba, 2° Floor. Box 134.Avenida Menendez Pidal s/n, 14004, Córdoba, Spain.
Saul Jimenez-RuizAnimal Health Department. Veterinary Science College, Universidad de Córdoba, 14014, Cordoba, Spain.
Jose C Gomez-VillamandosAnimal Pathology Department. Veterinary Science College, Universidad de Córdoba, Cordoba, Spain.
Antonio RiveroInfectious Diseases Unit. Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía de Córdoba. Universidad de Córdoba, 2° Floor. Box 134.Avenida Menendez Pidal s/n, 14004, Córdoba, Spain.

Funding

Instituto de Salud Carlos III PI16/01297Ministerio de Sanidad, Servicios Sociales e Igualdad RD12/0017/0012
6 · The paper itself

Abstract

backgroundIt has been shown that wildlife can serve as natural reservoirs of hepatitis E virus (HEV). The wild boar (Sus scrofa) is probably the main natural reservoir of HEV and could therefore represent an important route of transmission in Europe, especially in regions where game meat is widely consumed. We evaluated the prevalence of HEV infection in wild boar in the south of Spain, with the aim of identifying associated risk factors. A cross-sectional study that included hunted wild boar was carried out during the 2015/2016 hunting season (October 15 to February 15) in Andalusia (southern Spain). The outcome variable was HEV infection, defined as amplification of HEV RNA in serum by RT-PCR.

resultsA total of 142 animals, selected from 12 hunting areas, were included and formed the study population. Thirty-three wild boars (23.2%; 95% CI: 16.8%-30.7%) were positive for HEV infection. Prevalence peaked in October and November, then gradually declined until the end of December. After multivariate analysis, only hunting date was independently associated with HEV infection across sex and age.

conclusionsOur study found a relatively high prevalence of HEV infection in wild boar in the south of Spain, suggesting that prevalence may depend on the season when the animal is hunted. In consequence, the potential risk of zoonotic transmission could fluctuate.

Indexed as

Hepatitis E virusAnimalsAnimals, WildFemaleHepatitis EMalePrevalenceReverse Transcriptase Polymerase Chain ReactionSeasonsSpainSwineSwine DiseasesFoodborneHepatitis EPrevalenceSeasonalityWild boar

Identifiers

PMID29482645
PMCPMC5828074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.