Evidence map›Paper›PMID 29482597›Full record

Trial reportSubstance abuse treatment, prevention, and policy2018

Effects of substance use disorder on treatment process and outcome in a ten-session psychiatric treatment for borderline personality disorder.

Louise Penzenstadler, Stéphane Kolly, Stéphane Rothen, Yasser Khazaal, Ueli Kramer

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Substance abuse treatment, prevention, and policy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01896024 (Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01896024 nacompletednot on this map

Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder

TypeinterventionalSponsorUniversity of Lausanne HospitalsRan2010 to 2014Enrolled85ConditionsBorderline Personality DisorderArmsPsychiatric Management, Motive-oriented therapeutic relationship/Plan Analysis
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Louise PenzenstadlerGeneva University Hospitals, Service d'addictologie HUG, Rue de Grand-Pré 70c, 1202, Genève, Switzerland. Louise.E.Penzenstadler@hcuge.ch.ORCID 0000-0003-1379-0243
Stéphane KollyDepartment of Psychiatry, University Hospital of Lausanne, University of Lausanne, Lausanne, Switzerland.
Stéphane RothenGeneva University Hospitals, Service d'addictologie HUG, Rue de Grand-Pré 70c, 1202, Genève, Switzerland.
Yasser KhazaalGeneva University Hospitals, Service d'addictologie HUG, Rue de Grand-Pré 70c, 1202, Genève, Switzerland.
Ueli KramerDepartment of Psychiatry, University Hospital of Lausanne, University of Lausanne, Lausanne, Switzerland.
University of Geneva · CHUniversity Hospital of Lausanne · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 100014-134562
6 · The paper itself

Abstract

backgroundDual diagnosis is common in Borderline Personality Disorder (BPD), one of the most common being Substance Use Disorder (SUD). Previous studies have shown that general psychiatric management (GPM) was effective in reducing borderline symptoms. In the present study, we tested whether the short GPM was as effective in the BPD + SUD as in the BPD group.

methodsWe analysed a group of 99 patients presenting a BPD. 51 of these patients presented a SUD. The BPD group and the BPD + SUD group received a manual-based short variant of the GPM treatment. Previous studies have shown that a 10-session version of GPM was effective in reducing borderline symptoms at the end of the treatment (Psychother Psychosom 83:176-86, 2014).

resultsWe found no significant difference in the reduction of general symptoms, which diminished in both groups. The specific borderline symptoms were also reduced in both groups, but there was a slightly higher reduction of the borderline symptoms in the SUD group. The therapeutic alliance progressed positively in all groups. Moreover, the alliance increased more over time in the SUD group.

conclusionThe short variant of GPM seems to be effective in BPD treatment independently from the presence of SUD. Therefore, this treatment could be an effective entry-level treatment for patients with dual diagnosis as well as patients with BPD only. Further studies are needed to confirm efficacy and long-term outcome.

trial registrationThe trial was registered at ClinicalTrial.gov (identifier NCT01896024 ).

Indexed as

Behavior TherapyAdultBorderline Personality DisorderComorbidityDiagnosis, Dual (Psychiatry)FemaleHumansMaleMiddle AgedPsychotherapy, BriefSubstance-Related DisordersTreatment OutcomeYoung Adult

Identifiers

PMID29482597
PMCPMC5828425
OpenAlexW2792459222

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.