Evidence map›Paper›PMID 29482087›Full record

ArticleClinical biomechanics (Bristol, Avon)2018

The impact of hip implant alignment on muscle and joint loading during dynamic activities.

Casey A Myers, Peter J Laz, Kevin B Shelburne, Dana L Judd, Daniel N Huff, Joshua D Winters, Jennifer E Stevens-Lapsley, Paul J Rullkoetter

Registry-linked trialAbstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06603831 (Randomized, Prospective and Multicenter Clinical Study for the Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology and Orthopedic Surgery), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06603831 narecruitingnot on this mapstarted 2024, after this paper: background citation

Randomized, Prospective and Multicenter Clinical Study for the Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology and Orthopedic Surgery

TypeinterventionalSponsorCorporacion Parc TauliRan2024 to 2027Enrolled180ConditionsRadius, Deformity, Hip Osteoarthritis, Hip ArthritisArmspatients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Casey A MyersCenter for Orthopaedic Biomechanics, University of Denver, Denver, CO, USA. Electronic address: Casey.Myers@du.edu.
Peter J LazCenter for Orthopaedic Biomechanics, University of Denver, Denver, CO, USA.
Kevin B ShelburneCenter for Orthopaedic Biomechanics, University of Denver, Denver, CO, USA.
Dana L JuddPhysical Therapy Program, University of Colorado, Aurora, CO, USA.
Daniel N HuffDePuy Synthes Products, Inc., Warsaw, IN, USA.
Joshua D WintersPhysical Therapy Program, University of Colorado, Aurora, CO, USA.
Jennifer E Stevens-LapsleyPhysical Therapy Program, University of Colorado, Aurora, CO, USA; Geriatric Research Education and Clinical Center, VA Eastern Colorado Healthcare System, Denver, CO, USA.
Paul J RullkoetterCenter for Orthopaedic Biomechanics, University of Denver, Denver, CO, USA.

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
University of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1M
Improving Rehabilitation Outcomes After Total Hip ArthroplastyI01RX002251 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI STEVENS-LAPSLEY, JENNIFER E. · 2017 to 2021
–
NCATS NIH HHS UL1 TR001082RRD VA I01 RX002251
6 · The paper itself

Abstract

backgroundComponent alignment is an important consideration in total hip arthroplasty. The impact of changes in alignment on muscle forces and joint contact forces during dynamic tasks are not well understood, and have the potential to influence surgical decision making. The objectives of this study were to assess the impact of femoral head/stem and cup component placement on hip muscle and joint contact forces during tasks of daily living and to identify which alignment parameters have the greatest impact on joint loading.

methodsUsing a series of strength-calibrated, subject-specific musculoskeletal models of patients performing gait, sit-to-stand and step down tasks, component alignments were perturbed and joint contact and muscle forces evaluated.

findingsBased on the range of alignments reported clinically, variation in head/stem anteversion-retroversion had the largest impact of any degree of freedom throughout all three tasks; average contact forces 413.5 (319.1) N during gait, 262.7 (256.4) N during sit to stand, and 572.7 (228.1) N during the step down task. The sensitivity of contact force to anteversion-retroversion of the head/stem was 31.5 N/° for gait, which was similar in magnitude to anterior-posterior position of the cup (34.6 N/m for gait). Additionally, superior-inferior cup alignment resulted in 16.4 (4.9)° of variation in the direction of the hip joint contact force across the three tasks, with the most inferior cup placements moving the force vector towards the cup equator at the point of peak joint contact force.

interpretationA quantitative understanding of the impact and potential tradeoffs when altering component alignment is valuable in supporting surgical decision making.

Indexed as

Arthroplasty, Replacement, HipAdultAgedBiomechanical PhenomenaFemaleFemur HeadGaitHipHip JointHip ProsthesisHumansMaleMiddle AgedMuscle, SkeletalOsteoarthritisHip arthroplastyImplant alignmentJoint mechanicsMuscle forceMusculoskeletal modeling

Identifiers

PMID29482087
PMCPMC5890933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.