Evidence map›Paper›PMID 29480879›Full record

ArticleMedicine2018

Candida pneumonia with severe clinical course, recovery with antifungal therapy and unusual pathologic findings: A case report.

Josephine Kam Tai Dermawan, Subha Ghosh, M Kelly Keating, K V Gopalakrishna, Sanjay Mukhopadhyay

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Isolation ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  4. Clinical case reports · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. InvasiveAutopsy & case reports · 2023
    Article
  9. First Isolation ofPathogens (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. First Reported Case ofCase reports in cardiology · 2020
    Article
  15. Candida Pneumonia: An Innocent Bystander or a Silent Killer?Medical principles and practice : international journal of the Kuwait University, Health Science Centre
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Josephine Kam Tai DermawanDepartment of Pathology, Pathology and Laboratory Medicine Institute Imaging Institute, Cleveland Clinic Infectious Disease Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia Infectious Disease, Fairview Hospital, Cleveland Clinic, Cleveland, Ohio.
Subha Ghosh
M Kelly Keating
K V Gopalakrishna
Sanjay Mukhopadhyay
DNA Medicine Institute (United States) · USCenters for Disease Control and Prevention · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandida is frequently isolated from the respiratory tract and usually reflects airway colonization. True Candida pneumonia is rare. Our aim is to document a case of Candida pneumonia confirmed by cultures, molecular techniques, and surgical lung biopsy, and to highlight a previously unreported pathologic manifestation of this infection. CASE SUMMARY: A 59-year-old man with a history of chronic obstructive pulmonary disease (COPD) presented with dry cough, low-grade fever, and progressive dyspnea. He was eventually diagnosed with sarcoidosis based on bilateral lung infiltrates and granulomas in a transbronchial biopsy. His condition worsened after immunosuppression, prompting surgical lung biopsy, which revealed suppurative granulomas containing Candida albicans, confirmed by cultures and polymerase chain reaction. Despite multiple episodes of respiratory failure and a prolonged course in intensive care, he recovered fully after antifungal therapy and is currently alive with COPD-related dyspnea 3 years after his initial presentation.

conclusionCandida can rarely cause clinically significant pneumonia in adults, and should be considered in the differential diagnosis of suppurative granulomas in the lung.

Indexed as

Candida albicansAntifungal AgentsCandidiasisCritical CareDiagnosis, DifferentialHumansMaleMiddle AgedPneumoniaAntifungal Agents

Identifiers

PMID29480879
PMCPMC5943866
OpenAlexW2784010853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.