Evidence map›Paper›PMID 29480573›Full record

ArticleInternational journal of geriatric psychiatry2018

Persistence of depressive symptoms and gait speed recovery in older adults after hip fracture.

Alan M Rathbun, Michelle D Shardell, Elizabeth A Stuart, Ann L Gruber-Baldini, Denise Orwig, Glenn V Ostir, Gregory E Hicks, Marc C Hochberg, Jay Magaziner

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Alan M RathbunGeriatric Research, Education and Clinical Center, VA Maryland Health Care System, Baltimore, MD, USA.ORCID 0000-0003-3611-5494
Michelle D ShardellTranslational Gerontology Branch, National Institutes on Aging, Baltimore, MD, USA.
Elizabeth A StuartDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ann L Gruber-BaldiniDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Denise OrwigDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Glenn V OstirDepartment of Health Promotion and Behavior, University of Georgia College of Public Health, Athens, GA, USA.
Gregory E HicksDepartment of Physical Therapy, University of Delaware College of Health Sciences, Newark, DE, USA.
Marc C HochbergDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Jay MagazinerDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · USDepartment of Behavioral Health · USGeorgia College & State University · USJohns Hopkins University · USNational Institute on Aging · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
RESEARCH TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000262 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ANN L GRUBER-BALDINI, DENISE L ORWIG · 1998 to 2026
$8.2M
The Epidemiology of Bone Strength and Muscle Composition After Hip Fracture in MeR01AG029315 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 2007 to 2011
$4.1M
NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG029315NIA NIH HHS R37 AG009901NIA NIH HHS T32 AG000262
6 · The paper itself

Abstract

objectiveDepression after hip fracture in older adults is associated with worse physical performance; however, depressive symptoms are dynamic, fluctuating during the recovery period. The study aim was to determine how the persistence of depressive symptoms over time cumulatively affects the recovery of physical performance.

methodsMarginal structural models estimated the cumulative effect of persistence of depressive symptoms on gait speed during hip fracture recovery among older adults (n = 284) enrolled in the Baltimore Hip Studies 7th cohort. Depressive symptoms at baseline and at 2-month and 6-month postadmission for hip fracture were evaluated by using the Center for Epidemiological Studies Depression Scale, and persistence of symptoms was assessed as a time-averaged severity lagged to standardized 3 m gait speed at 2, 6, and 12 months.

resultsA 1-unit increase in time-averaged Center for Epidemiological Studies Depression score was associated with a mean difference in gait speed of -0.0076 standard deviations (95% confidence interval [CI]: -0.0184, 0.0032; P = .166). The association was largest in magnitude from baseline to 6 months: -0.0144 standard deviations (95% CI: -0.0303, 0.0015; P = 0.076). Associations for the other time intervals were smaller: -0.0028 standard deviations (95% CI: -0.0138, 0.0083; P = .621) at 2 months and -0.0121 standard deviations (95% CI: -0.0324, 0.0082; P = .238) at 12 months.

conclusionAlthough not statistically significant, the magnitude of the numerical estimates suggests that expressing more depressive symptoms during the first 6 months after hip fracture has a meaningful impact on functional recovery.

Indexed as

AgedAged, 80 and overBaltimoreCohort StudiesDepressive DisorderFemaleGaitHip FracturesHumansMaleMiddle AgedPsychiatric Status Rating ScalesRecovery of FunctionWalking Speedagingdepressive symptomship fracturephysical performance

Identifiers

PMID29480573
PMCPMC5995625
OpenAlexW2790553394

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.