ArticleEnvironmental science and pollution research international2018
Early life exposure of zebrafish (Danio rerio) to synthetic pyrethroids and their metabolites: a comparison of phenotypic and behavioral indicators and gene expression involved in the HPT axis and innate immune system.
Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Developmental Toxicity and Thyroid-Disrupting Effects of Combined Exposure to Pb(II) andToxics · 2026Article
- Review
- Cypermethrin: An Emerging Pollutant and Its Adverse Effect on Fish Health and some Preventive Approach-A Review.Indian journal of microbiology · 2024Review
- Enantioselective Toxicity of Tetramethrin to Different Developmental Stages of Zebrafish (Toxics · 2024Article
- Association between pesticide exposure and thyroid function: analysis of Chinese and NHANES databases.Frontiers in public health · 2024Article
- An Overview on the Potential Hazards of Pyrethroid Insecticides in Fish, with Special Emphasis on Cypermethrin Toxicity.Animals : an open access journal from MDPI · 2021Review
- Exposure to permethrin or chlorpyrifos causes differential dose- and time-dependent behavioral effects at early larval stages of an endangered teleost species.Endangered species research · 2021Article
- Biochemical responses of a freshwater fish Cirrhinus mrigala exposed to tris(2-chloroethyl) phosphate (TCEP).Environmental science and pollution research international · 2020Article
- An epigenome-wide association study of ambient pyrethroid pesticide exposures in California's central valley.International journal of hygiene and environmental health · 2020Article
- Core-satellite surface imprinting polymer-based pipette tip solid-phase extraction for the colorimetric determination of pyrethroid metabolite.Mikrochimica acta · 2020Article
- Influence of Nanomolar Deltamethrin on the Hallmarks of Primary Cultured Cortical Neuronal Network and the Role of Ryanodine Receptors.Environmental health perspectives · 2019Article
- Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data.Frontiers in endocrinology · 2019Review
- Pyrethroid pesticide metabolite, 3-PBA, in soils: method development and application to real agricultural soils.Environmental science and pollution research international · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Ecotoxicological studies have revealed the association between synthetic pyrethroid (SP) exposure and aquatic toxicity in fish; however, research on the toxic effects of SP metabolites is still limited. In this study, the toxicity of two SPs (permethrin (PM) and β-cypermethrin (β-CP)) and their three metabolites (3-phenoxybenzoic alcohol (PBCOH), 3-phenoxybenzaldehyde (PBCHO), and 3-phenoxybenzoic acid (PBCOOH)) towards zebrafish embryos and larvae was evaluated. Both SPs and their metabolites exhibited significant developmental toxicities, caused abnormal vascular development, and changed locomotor activities in larvae. The alteration of gene expression involved in the thyroid system and the innate immune system indicated that SPs and their three metabolites have the potency to induce thyroid disruption and trigger an immune response. The results from the present study suggest that SP metabolites could induce multiple toxic responses similar to parent compounds, and their toxicity should be considered for improving the understanding of environmental risks of SPs.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.