Evidence map›Paper›PMID 29480214›Full record

ReviewJournal of neuromuscular diseases

Muscle Cells Fix Breaches by Orchestrating a Membrane Repair Ballet.

Florian Barthélémy, Aurélia Defour, Nicolas Lévy, Martin Krahn, Marc Bartoli

Abstract readReview
In one paragraph

Review in Journal of neuromuscular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Eccentric Exercise and Muscle Damage: An Introductory Guide.Journal of functional morphology and kinesiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. When SizeBiomedicines · 2023
    Article
  10. Review
  11. Article
  12. Otoferlin as a multirole CaFrontiers in cellular neuroscience · 2023
    Review
  13. Article
  14. Fusion and beyond: Satellite cell contributions to loading-induced skeletal muscle adaptation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Review
  15. Annexins and Membrane Repair Dysfunctions in Muscular Dystrophies.International journal of molecular sciences · 2021
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Florian BarthélémyMicrobiology Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA.
Aurélia DefourAix Marseille University, MMG, INSERM, Marseille, France.
Nicolas LévyAix Marseille University, MMG, INSERM, Marseille, France.
Martin KrahnAix Marseille University, MMG, INSERM, Marseille, France.
Marc BartoliAix Marseille University, MMG, INSERM, Marseille, France.

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
NIAMS NIH HHS U54 AR052646
6 · The paper itself

Abstract

Skeletal muscle undergoes many micro-membrane lesions at physiological state. Based on their sizes and magnitude these lesions are repaired via different complexes on a specific spatio-temporal manner. One of the major repair complex is a dysferlin-dependent mechanism. Accordingly, mutations in the DYSF gene encoding dysferlin results in the development of several muscle pathologies called dysferlinopathies, where abnormalities of the membrane repair process have been characterized in patients and animal models. Recent efforts have been deployed to decipher the function of dysferlin, they shed light on its direct implication in sarcolemma resealing after injuries. These discoveries served as a strong ground to design therapeutic approaches for dysferlin-deficient patients. This review detailed the different partners and function of dysferlin and positions the sarcolemma repair in normal and pathological conditions.

Indexed as

AnimalsAnnexinsCarrier ProteinsDistal MyopathiesDysferlinHumansModels, AnimalMuscle Fibers, SkeletalMuscular AtrophyMuscular Dystrophies, Limb-GirdleMutationSarcolemmaTripartite Motif ProteinsAnnexinsCarrier ProteinsDysferlinTRIM72 protein, humanTripartite Motif ProteinsdysferlindystrophymembraneMusclemyopathy

Identifiers

PMID29480214
PMCPMC5836414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.