Evidence map›Paper›PMID 29480077›Full record

ArticleMolecular imaging

Reversible Electroporation-Mediated Liposomal Doxorubicin Delivery to Tumors Can Be Monitored With

Govindarajan Srimathveeravalli, Dalya Abdel-Atti, Carlos Pérez-Medina, Haruyuki Takaki, Stephen B Solomon, Willem J M Mulder, Thomas Reiner

Open access · goldAbstract read
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  4. Advances in nanomaterial-based targeted drug delivery systems.Frontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Govindarajan Srimathveeravalli1 Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Dalya Abdel-Atti1 Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Carlos Pérez-Medina3 Translational and Molecular Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Haruyuki Takaki4 Department of Radiology, Hyogo College of Medicine, Hyogo, Japan.
Stephen B Solomon1 Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Willem J M Mulder3 Translational and Molecular Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Thomas Reiner1 Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · USIcahn School of Medicine at Mount Sinai · USCornell University · USHyogo Medical University · JP

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Training and Career Development CoreU54CA132378 · NCI · CITY COLLEGE OF NEW YORK · PI Tim Alan Ahles, ADRIANA ESPINOSA · 2008 to 2026
$28.9M
Training and Career Development and Education CoreU54CA137788 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI ADRIANA ESPINOSA, FRANCESCA M GANY · 2008 to 2026
$28.1M
Radioiodinated Multifunctional PARP1 Imaging Probes for Diagnosis and TherapyR01CA204441 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI PILLARSETTY, NAGAVARAKISHORE · 2016 to 2020
$2.9M
PET/MRI to study nanotherapy in atherosclerosisR01HL125703 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2015 to 2018
$2.4M
A Surface Activable Nanoemulsion platform for Breast Cancer Diagnosis and TherapyR01CA155432 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2011 to 2015
$1.7M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA155432NCI NIH HHS R01 CA204441NCI NIH HHS U54 CA132378NCI NIH HHS U54 CA137788NHLBI NIH HHS R01 HL125703
6 · The paper itself

Abstract

Reversible electroporation (RE) can facilitate nanoparticle delivery to tumors through direct transfection and from changes in vascular permeability. We investigated a radiolabeled liposomal nanoparticle (

Indexed as

Drug Delivery SystemsCapillary PermeabilityCell Line, TumorDoxorubicinElectroporationHumansNanoparticlesNeoplasmsPolyethylene GlycolsPositron-Emission TomographyRadioisotopesRadiopharmaceuticalsZirconiumDoxorubicinliposomal doxorubicinPolyethylene GlycolsRadioisotopesRadiopharmaceuticalsZirconiumZirconium-89animal PETdrug deliverynanoparticle

Identifiers

PMID29480077
PMCPMC5833236
OpenAlexW2790083077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.