Evidence map›Paper›PMID 29479699›Full record

ArticleThe Journal of physiology2018

Brainstem catecholaminergic neurones and breathing control during postnatal development in male and female rats.

Luis Gustavo A Patrone, Vivian Biancardi, Danuzia A Marques, Kênia C Bícego, Luciane H Gargaglioni

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Locus coeruleus noradrenaline depletion and its differential impact on COProgress in neuro-psychopharmacology & biological psychiatry · 2024
    Article
  3. Article
  4. eLife · 2022
    Article
  5. Article
  6. A5 noradrenergic neurons and breathing control in neonate rats.Pflugers Archiv : European journal of physiology · 2021
    Article
  7. Unraveling the Mechanisms Underlying Irregularities in Inspiratory Rhythm Generation in a Mouse Model of Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luis Gustavo A PatroneDepartment of Animal Morphology and Physiology, Sao Paulo State University - UNESP/FCAV at Jaboticabal, SP, Brazil.
Vivian BiancardiDepartment of Animal Morphology and Physiology, Sao Paulo State University - UNESP/FCAV at Jaboticabal, SP, Brazil.
Danuzia A MarquesDepartment of Animal Morphology and Physiology, Sao Paulo State University - UNESP/FCAV at Jaboticabal, SP, Brazil.
Kênia C BícegoDepartment of Animal Morphology and Physiology, Sao Paulo State University - UNESP/FCAV at Jaboticabal, SP, Brazil.
Luciane H GargaglioniDepartment of Animal Morphology and Physiology, Sao Paulo State University - UNESP/FCAV at Jaboticabal, SP, Brazil.ORCID 0000-0003-4097-5286
Universidade Estadual Paulista (Unesp) · BR

Funding

CNPq 131660/2013-6CNPq 442560/2014-1São Paulo Research Foundation 2016/24577-3
6 · The paper itself

Abstract

key pointsThe brainstem catecholaminergic (CA) modulation on ventilation changes with development. We determined the role of the brainstem CA system in ventilatory control under normocapnic and hypercapnic conditions during different phases of development [postnatal day (P)7-8, P14-15 and P20-21] in male and female Wistar rats. Brainstem CA neurones produce a tonic inhibitory drive that affects breathing frequency in P7-8 rats and provide an inhibitory drive during hypercapnic conditions in both males and females at P7-8 and P14-15. In pre-pubertal rats, brainstem CA neurones become excitatory for the CO ABSTRACT: The respiratory network undergoes significant development during the postnatal phase, including the maturation of the catecholaminergic (CA) system. However, postnatal development of this network and its effect on the control of pulmonary ventilation (

Indexed as

Adrenergic NeuronsAnimalsAnimals, NewbornBrain StemFemaleHypercapniaMaleNeuronsOxygen ConsumptionPulmonary VentilationRats, WistarRespirationcatecholaminechemosensitivitymedullaneonatepons

Identifiers

PMID29479699
PMCPMC6068229
OpenAlexW2885950368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.