Evidence map›Paper›PMID 29479565›Full record

ArticleHepatoma research2018

Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer.

Taoyang Chen, Gengsun Qian, Chunsun Fan, Yan Sun, Jinbing Wang, Peixin Lu, Xuefeng Xue, Yan Wu, Qinan Zhang, Yan Jin and 6 more

Abstract read
In one paragraph

Article in Hepatoma research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Taoyang ChenDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Gengsun QianState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200032, China.
Chunsun FanDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Yan SunDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Jinbing WangDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Peixin LuDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Xuefeng XueDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Yan WuDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Qinan ZhangDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Yan JinState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200032, China.
Yiqian WuState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200032, China.
Yu GanState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200032, China.
Jianquan LuDepartment of Etiology, Qidong Liver Cancer Institute, Qidong People's Hospital, Qidong, 226200, Jiangsu, China.
Thomas W KenslerEnvironmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
John D GroopmanEnvironmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Hong TuState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200032, China.

Funding

Validation and Application of Risk, Biomarkers in Human StudiesP01ES006052 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI GROOPMAN, JOHN D · 1993 to 2012
$22.6M
Targeting Nrf2 for Cancer ChemopreventionR35CA197222 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KENSLER, THOMAS W · 2015 to 2021
$6.7M
Detoxication of Air Pollutants in Humans with a Broccoli SupplementR01CA190610 · NCI · JOHNS HOPKINS UNIVERSITY · PI GROOPMAN, JOHN D · 2015 to 2019
$2.1M
NCI NIH HHS R01 CA190610NCI NIH HHS R35 CA197222NIEHS NIH HHS P01 ES006052
6 · The paper itself

Abstract

Qidong hepatitis B virus (HBV) infection cohort (QBC) is a prospective community-based study designed to investigate causative factors of primary liver cancer (PLC) in Qidong, China, where both PLC and HBV infection are highly endemic. Residents aged 20-65 years, living in seven townships of Qidong, were surveyed using hepatitis B surface antigen (HBsAg) serum test and invited to participate in QBC from June 1991 to December 1991. A total of 852 and 786 participants were enrolled in HBsAg-positive and HBsAg-negative sub-cohorts in May 1992, respectively. All participants were actively followed up in person, received HBsAg, alanine aminotransferase (ALT), alpha-fetoprotein (AFP) tests and upper abdominal ultrasonic examination, and donated blood and urine samples once or twice a year. The total response rate was 99.6%, and the number of incident PLC was 201 till the end of February 2017. The ratio of incidence rates was 12.32 (95% confidence interval[CI]=7.16-21.21,

Indexed as

hepatitis B virusprimary liver cancerProspective cohort

Identifiers

PMID29479565
PMCPMC5824723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.