Evidence map›Paper›PMID 29479563›Full record

ArticleTomography (Ann Arbor, Mich.)2017

Imaging Lung Cancer by Using Chemical Exchange Saturation Transfer MRI With Retrospective Respiration Gating.

Kyle M Jones, Carol A Stuehm, Charles C Hsu, Phillip H Kuo, Mark D Pagel, Edward A Randtke

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kyle M JonesDepartment of Biomedical Engineering, University of Arizona, Tucson, AZ.
Carol A StuehmDepartment of Medical Imaging, University of Arizona, Tucson, AZ.
Charles C HsuDepartment of Radiation Oncology, University of Arizona, Tucson, AZ.
Phillip H KuoDepartment of Medical Imaging, University of Arizona, Tucson, AZ.
Mark D PagelDepartment of Medical Imaging, University of Arizona, Tucson, AZ.
Edward A RandtkeDepartment of Medical Imaging, University of Arizona, Tucson, AZ.
University of Arizona · USUniversity of Arizona Cancer Center

Funding

MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCHT32HL066988 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N, O'REILLY, MICHAEL A · 2001 to 2021
$8.1M
Cardiovascular Biomedical Engineering Training GrantT32HL007955 · NHLBI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2001 to 2020
$5.1M
Detection of in vivo enzyme activities with CEST MRIR01CA169774 · NCI · UNIVERSITY OF ARIZONA · PI CARDENAS-RODRIGUEZ, JULIO · 2012 to 2016
$2.5M
Early phase clinical trial for imaging tumor acidosis in breast cancer patients using acidoCEST MRIR01CA197029 · NCI · UNIVERSITY OF ARIZONA · PI CARDENAS-RODRIGUEZ, JULIO · 2015 to 2016
$701k
NCI NIH HHS R01 CA169774NCI NIH HHS R01 CA197029NHLBI NIH HHS T32 HL007955NHLBI NIH HHS T32 HL066988
6 · The paper itself

Abstract

Performing chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) in lung tissue is difficult because of motion artifacts. We, therefore, developed a CEST MRI acquisition and analysis method that performs retrospective respiration gating. Our method used an acquisition scheme with a short 200-millisecond saturation pulse that can accommodate the timing of the breathing cycle, and with saturation applied at frequencies in 0.03-ppm intervals. The Fourier transform of each image was used to calculate the difference in phase angle between adjacent pixels in the longitudinal direction of the respiratory motion. Additional digital filtering techniques were used to evaluate the breathing cycle, which was used to construct CEST spectra from images during quiescent periods. Results from CEST MRI with and without respiration gating analysis were used to evaluate the asymmetry of the magnetization transfer ratio (MTR

Indexed as

APT MRICEST MRIlung cancerlung imaging

Identifiers

PMID29479563
PMCPMC5823523
OpenAlexW2775806787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.