Evidence map›Paper›PMID 29479533›Full record

ArticleMatters2017

BIN1 localization is distinct from Tau tangles in Alzheimer's disease.

Pierre De Rossi, Virginie Buggia-Prevot, Robert J Andrew, Sofia V Krause, Elizabeth Woo, Peter T Nelson, Peter Pytel, Gopal Thinakaran

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Matters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Astrocyte and oligodendrocyte pathology in Alzheimer's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pierre De RossiDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Virginie Buggia-PrevotDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Robert J AndrewDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Sofia V KrauseDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Elizabeth WooDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Peter T NelsonDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Peter PytelDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
Gopal ThinakaranDepartment of Neurobiology, The University of Chicago; Sanders-Brown Center on Aging and Department of Physiology, University of Kentucky (US); Department of Pathology, The University of Chicago; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago.
University of Chicago · US

Funding

University of Kentucky Alzheimer's Disease Core Center - Biomarker CoreP30AG028383 · NIA · UNIVERSITY OF KENTUCKY · PI GOLD, BRIAN TIMOTHY, VAN ELDIK, LINDA J · 2006 to 2020
$23.3M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Cell autonomous and non-cell autonomous roles of the GWAS risk factor BIN1 in Alzheimer's disease neuropathologyRF1AG054223 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI THINAKARAN, GOPAL · 2016 to 2016
$2.9M
Multi-purpose Superresolution Microscope for Core FacilityS10OD010649 · OD · UNIVERSITY OF CHICAGO · PI THINAKARAN, GOPAL · 2012 to 2012
$511k
NCATS NIH HHS UL1 TR000430NIA NIH HHS P30 AG028383NIA NIH HHS RF1 AG054223NIH HHS S10 OD010649
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’S DiseaseBIN1OligodendrocytesTangleTau Pathology

Identifiers

PMID29479533
PMCPMC5823513
OpenAlexW2579723938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.